Evaluations of buparvaquone as a treatment for equine babesiosis (Babesia equi).

J. L. Zaugg, V Michael Lane

Research output: Contribution to journalArticle

23 Scopus citations

Abstract

We evaluated the efficacy of buparvaquone in eliminating Babesia equi of European origin in carrier horses and in experimentally infected splenectomized ponies. When administered at the rate of 2.5 mg/kg of body weight, IM, 4 times at 96-hour intervals, buparvaquone was effective in eliminating B equi carrier infection in 1 horse. Such results could not be repeated at the same dosage or at 3.5 or 5 mg/kg, IM. Buparvaquone given at the rate of 4 to 6 mg/kg IV and/or IM was therapeutically effective in 4 of 5 acute B equi infections in splenectomized ponies. The treated ponies became carriers.

Original languageEnglish (US)
Pages (from-to)782-785
Number of pages4
JournalAmerican Journal of Veterinary Research
Volume50
Issue number5
StatePublished - May 1989
Externally publishedYes

ASJC Scopus subject areas

  • veterinary(all)

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