Abstract
We evaluated the efficacy of buparvaquone in eliminating Babesia equi of European origin in carrier horses and in experimentally infected splenectomized ponies. When administered at the rate of 2.5 mg/kg of body weight, IM, 4 times at 96-hour intervals, buparvaquone was effective in eliminating B equi carrier infection in 1 horse. Such results could not be repeated at the same dosage or at 3.5 or 5 mg/kg, IM. Buparvaquone given at the rate of 4 to 6 mg/kg IV and/or IM was therapeutically effective in 4 of 5 acute B equi infections in splenectomized ponies. The treated ponies became carriers.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 782-785 |
| Number of pages | 4 |
| Journal | American Journal of Veterinary Research |
| Volume | 50 |
| Issue number | 5 |
| State | Published - May 1989 |
| Externally published | Yes |
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ASJC Scopus subject areas
- veterinary(all)
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Evaluations of buparvaquone as a treatment for equine babesiosis (Babesia equi). / Zaugg, J. L.; Lane, V Michael.
In: American Journal of Veterinary Research, Vol. 50, No. 5, 05.1989, p. 782-785.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Evaluations of buparvaquone as a treatment for equine babesiosis (Babesia equi).
AU - Zaugg, J. L.
AU - Lane, V Michael
PY - 1989/5
Y1 - 1989/5
N2 - We evaluated the efficacy of buparvaquone in eliminating Babesia equi of European origin in carrier horses and in experimentally infected splenectomized ponies. When administered at the rate of 2.5 mg/kg of body weight, IM, 4 times at 96-hour intervals, buparvaquone was effective in eliminating B equi carrier infection in 1 horse. Such results could not be repeated at the same dosage or at 3.5 or 5 mg/kg, IM. Buparvaquone given at the rate of 4 to 6 mg/kg IV and/or IM was therapeutically effective in 4 of 5 acute B equi infections in splenectomized ponies. The treated ponies became carriers.
AB - We evaluated the efficacy of buparvaquone in eliminating Babesia equi of European origin in carrier horses and in experimentally infected splenectomized ponies. When administered at the rate of 2.5 mg/kg of body weight, IM, 4 times at 96-hour intervals, buparvaquone was effective in eliminating B equi carrier infection in 1 horse. Such results could not be repeated at the same dosage or at 3.5 or 5 mg/kg, IM. Buparvaquone given at the rate of 4 to 6 mg/kg IV and/or IM was therapeutically effective in 4 of 5 acute B equi infections in splenectomized ponies. The treated ponies became carriers.
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M3 - Article
C2 - 2729726
AN - SCOPUS:0024672017
VL - 50
SP - 782
EP - 785
JO - American Journal of Veterinary Research
JF - American Journal of Veterinary Research
SN - 0002-9645
IS - 5
ER -