Evaluation of the spatial resolution characteristics of a cone-beam breast CT scanner

Alexander L C Kwan, John M Boone, Kai Yang, Shih Ying Huang

Research output: Contribution to journalArticle

114 Citations (Scopus)

Abstract

The purpose of this study was to examine the spatial resolution of a prototype pendant-geometry cone-beam breast computed tomography (CT) system. Modulation transfer functions (MTFs) of the reconstructed image in the coronal (x and y) plane were computed as a function of the cone angle, the radial distance from the axis of rotation, the size of the reconstruction matrix, the back-projection filter used, and the number of projections acquired for the reconstruction. The results show that the cone angle and size of the reconstruction matrix have minimal impact on the MTF, while the MTF degraded radially from the axis of rotation (from 0.76 at 2.6 mm from axis of rotation down to 0.37 at 76.9 mm from axis of rotation at f=0.5 mm-1). The Ramp reconstruction filter increases the MTF near the axis of rotation relative to the Shepp-Logan filter, while an increase in the number of projections from 500 to 1000 increased the MTF near the periphery of the reconstructed image. The MTF in the z direction (anterior-posterior direction) was also evaluated. The z -direction MTF values tend to be higher when compared to the coronal MTF (0.85 at f=0.5 mm-1), and tend to be very constant throughout the coronal plane direction. The results suggest that an increase in the MTF for the prototype breast CT system is possible by optimizing various scanning and reconstruction parameters.

Original languageEnglish (US)
Pages (from-to)275-281
Number of pages7
JournalMedical Physics
Volume34
Issue number1
DOIs
StatePublished - Jan 2007

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Cone-Beam Computed Tomography
Breast
Architectural Accessibility
Tomography
Direction compound

Keywords

  • Breast imaging
  • Computed tomography
  • Cone beam
  • Modulation transfer function
  • MTF

ASJC Scopus subject areas

  • Biophysics

Cite this

Evaluation of the spatial resolution characteristics of a cone-beam breast CT scanner. / Kwan, Alexander L C; Boone, John M; Yang, Kai; Huang, Shih Ying.

In: Medical Physics, Vol. 34, No. 1, 01.2007, p. 275-281.

Research output: Contribution to journalArticle

Kwan, Alexander L C ; Boone, John M ; Yang, Kai ; Huang, Shih Ying. / Evaluation of the spatial resolution characteristics of a cone-beam breast CT scanner. In: Medical Physics. 2007 ; Vol. 34, No. 1. pp. 275-281.
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