Evaluation of the prevalence of infections in cats after renal transplantation: 169 Cases (1987-2003)

Elissa Kadar, Jane E Sykes, Philip H Kass, Lynda Bernsteen, Clare R. Gregory, Andrew E. Kyles

Research output: Contribution to journalArticle

31 Scopus citations

Abstract

Objective - To determine the prevalence of infections developing postoperatively, document the contribution of infection to increased risk of death, and identify risk factors associated with the development of infectious complications in cats after renal transplantation. Design - Retrospective study. Animals - 169 cats that received renal allograft transplants. Procedures - Medical records of cats receiving renal transplants at the University of California from January 1987 through December 2003 were reviewed. Results - 47 infections developed in 43 of 169 cats. Bacterial infections were most common (25/47 cats), followed by viral (13/47), fungal (6/47), and protozoal (3/47) infections. The median duration from transplant surgery to development of infection was 2.5 months. Infection was the second most common cause of death after acute rejection of the transplant, accounting for 14% of deaths overall. Cats with concurrent diabetes mellitus had a significantly increased risk of developing an infection after renal transplantation. Sex, increasing age, concurrent neoplasia, and previous treatment for transplant rejection were not associated with development of infection. Conclusions and Clinical Relevance - Infection was a common complication and an important cause of death or euthanasia in cats after renal transplantation. Development of diabetes mellitus after transplantation significantly increased the risk of infection.

Original languageEnglish (US)
Pages (from-to)948-953
Number of pages6
JournalJournal of the American Veterinary Medical Association
Volume227
Issue number6
DOIs
StatePublished - Sep 15 2005

ASJC Scopus subject areas

  • veterinary(all)

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