Evaluation of the induction and recovery characteristics of anesthesia with desflurane in cats

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Abstract

Objective - To qualitatively and quantitatively evaluate the characteristics of desflurane with regard to the induction of and recovery from anesthesia in cats. Animals - 6 cats. Procedure - Anesthesia was induced and maintained with desflurane in oxygen. Individual minimum alveolar concentration (MAC) values were determined-anesthesia was maintained at 1.25 X MAC for a total anesthesia time (including MAC determination) of 5 hours. Cats were allowed to recover from anesthesia. Induction and recovery periods were video recorded and later scored by use of a grading scale from 0 to 100 (100 being the best outcome). Timing of events was recorded. Results - The MAC of desflurane was 10.27 ± 1.06%, and mean dose was 5.6 ± 0.2 MAC-hours. Times to loss of coordination, recumbency, and endotracheal intubation were 1.3 ± 0.4, 2.3 ± 0.3, and 6.4 ± 1.1 minutes, respectively. Median score for quality of anesthetic induction was 93 (range, 91 to 94). Times to first movement, extubation, standing, and ability to jump and land with coordination were 2.8 ± 1.0, 3.8 ± 0.5, 14.3 ± 3.9, and 26.4 ± 5.1 minutes, respectively. Alveolar washout of desflurane was rapid. Median score for quality of anesthetic recovery was 94 (range, 86 to 96). Conclusions and Clinical Relevance - Desflurane was associated with rapid induction of and recovery from anesthesia in cats; assessors rated the overall quality of induction and recovery as excellent. Results appear to support the use of desflurane for induction and maintenance of anesthesia in healthy cats.

Original languageEnglish (US)
Pages (from-to)748-751
Number of pages4
JournalAmerican Journal of Veterinary Research
Volume65
Issue number6
DOIs
StatePublished - Jun 2004

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anesthesia
Cats
Anesthesia
cats
anesthetics
Anesthetics
Intratracheal Intubation
desflurane
Maintenance
Oxygen
oxygen
dosage
animals

ASJC Scopus subject areas

  • veterinary(all)

Cite this

@article{1365ce7d3a9f467c9b6ec2221117d4c2,
title = "Evaluation of the induction and recovery characteristics of anesthesia with desflurane in cats",
abstract = "Objective - To qualitatively and quantitatively evaluate the characteristics of desflurane with regard to the induction of and recovery from anesthesia in cats. Animals - 6 cats. Procedure - Anesthesia was induced and maintained with desflurane in oxygen. Individual minimum alveolar concentration (MAC) values were determined-anesthesia was maintained at 1.25 X MAC for a total anesthesia time (including MAC determination) of 5 hours. Cats were allowed to recover from anesthesia. Induction and recovery periods were video recorded and later scored by use of a grading scale from 0 to 100 (100 being the best outcome). Timing of events was recorded. Results - The MAC of desflurane was 10.27 ± 1.06{\%}, and mean dose was 5.6 ± 0.2 MAC-hours. Times to loss of coordination, recumbency, and endotracheal intubation were 1.3 ± 0.4, 2.3 ± 0.3, and 6.4 ± 1.1 minutes, respectively. Median score for quality of anesthetic induction was 93 (range, 91 to 94). Times to first movement, extubation, standing, and ability to jump and land with coordination were 2.8 ± 1.0, 3.8 ± 0.5, 14.3 ± 3.9, and 26.4 ± 5.1 minutes, respectively. Alveolar washout of desflurane was rapid. Median score for quality of anesthetic recovery was 94 (range, 86 to 96). Conclusions and Clinical Relevance - Desflurane was associated with rapid induction of and recovery from anesthesia in cats; assessors rated the overall quality of induction and recovery as excellent. Results appear to support the use of desflurane for induction and maintenance of anesthesia in healthy cats.",
author = "Barter, {Linda S} and Jan Ilkiw and Pypendop, {Bruno H} and Eugene Steffey",
year = "2004",
month = "6",
doi = "10.2460/ajvr.2004.65.748",
language = "English (US)",
volume = "65",
pages = "748--751",
journal = "American Journal of Veterinary Research",
issn = "0002-9645",
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T1 - Evaluation of the induction and recovery characteristics of anesthesia with desflurane in cats

AU - Barter, Linda S

AU - Ilkiw, Jan

AU - Pypendop, Bruno H

AU - Steffey, Eugene

PY - 2004/6

Y1 - 2004/6

N2 - Objective - To qualitatively and quantitatively evaluate the characteristics of desflurane with regard to the induction of and recovery from anesthesia in cats. Animals - 6 cats. Procedure - Anesthesia was induced and maintained with desflurane in oxygen. Individual minimum alveolar concentration (MAC) values were determined-anesthesia was maintained at 1.25 X MAC for a total anesthesia time (including MAC determination) of 5 hours. Cats were allowed to recover from anesthesia. Induction and recovery periods were video recorded and later scored by use of a grading scale from 0 to 100 (100 being the best outcome). Timing of events was recorded. Results - The MAC of desflurane was 10.27 ± 1.06%, and mean dose was 5.6 ± 0.2 MAC-hours. Times to loss of coordination, recumbency, and endotracheal intubation were 1.3 ± 0.4, 2.3 ± 0.3, and 6.4 ± 1.1 minutes, respectively. Median score for quality of anesthetic induction was 93 (range, 91 to 94). Times to first movement, extubation, standing, and ability to jump and land with coordination were 2.8 ± 1.0, 3.8 ± 0.5, 14.3 ± 3.9, and 26.4 ± 5.1 minutes, respectively. Alveolar washout of desflurane was rapid. Median score for quality of anesthetic recovery was 94 (range, 86 to 96). Conclusions and Clinical Relevance - Desflurane was associated with rapid induction of and recovery from anesthesia in cats; assessors rated the overall quality of induction and recovery as excellent. Results appear to support the use of desflurane for induction and maintenance of anesthesia in healthy cats.

AB - Objective - To qualitatively and quantitatively evaluate the characteristics of desflurane with regard to the induction of and recovery from anesthesia in cats. Animals - 6 cats. Procedure - Anesthesia was induced and maintained with desflurane in oxygen. Individual minimum alveolar concentration (MAC) values were determined-anesthesia was maintained at 1.25 X MAC for a total anesthesia time (including MAC determination) of 5 hours. Cats were allowed to recover from anesthesia. Induction and recovery periods were video recorded and later scored by use of a grading scale from 0 to 100 (100 being the best outcome). Timing of events was recorded. Results - The MAC of desflurane was 10.27 ± 1.06%, and mean dose was 5.6 ± 0.2 MAC-hours. Times to loss of coordination, recumbency, and endotracheal intubation were 1.3 ± 0.4, 2.3 ± 0.3, and 6.4 ± 1.1 minutes, respectively. Median score for quality of anesthetic induction was 93 (range, 91 to 94). Times to first movement, extubation, standing, and ability to jump and land with coordination were 2.8 ± 1.0, 3.8 ± 0.5, 14.3 ± 3.9, and 26.4 ± 5.1 minutes, respectively. Alveolar washout of desflurane was rapid. Median score for quality of anesthetic recovery was 94 (range, 86 to 96). Conclusions and Clinical Relevance - Desflurane was associated with rapid induction of and recovery from anesthesia in cats; assessors rated the overall quality of induction and recovery as excellent. Results appear to support the use of desflurane for induction and maintenance of anesthesia in healthy cats.

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