Evaluation of the haemostatic profile in the pre- and post parturient mare, with particular focus on the perinatal period.

P. A. Gentry, B. F. Feldman, S. L. O'Neill, John E Madigan, J. G. Zinkl

Research output: Contribution to journalArticle

24 Scopus citations

Abstract

Various haemostatic analytes were systematically evaluated for four months pre-partum and five months post partum in 14 healthy mares. The plasma fibrinogen concentration and both Factor VIII:C and von Willebrand factor activity showed gradual increases from mid-gestation and reached maximal, or near maximal activity at parturition. These increases were paralleled by an increase in plasma fibronectin concentration, the appearance of fibrinogen degradation products, and a modest rise in antithrombin III concentration. In contrast, the activity of Factor VII and Factor IX, and the one-stage prothrombin (PT) time and the activated partial thromboplastin (APTT) time remained relatively constant throughout the pre- and post parturient period.

Original languageEnglish (US)
Pages (from-to)33-36
Number of pages4
JournalEquine Veterinary Journal
Volume24
Issue number1
StatePublished - Jan 1992

ASJC Scopus subject areas

  • veterinary(all)

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