Evaluation of the field efficacy of an avirulent live Lawsonia intracellularis vaccine in foals

N. Nogradi, N. M. Slovis, C. J. Gebhart, K. E. Wolfsdorf, J. L. McCracken, C. F. Scoggin, Philip H Kass, S. M. Mapes, B. Toth, M. L. Lundquist, Nicola Pusterla

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Equine proliferative enteropathy caused by Lawsonia intracellularis is an emerging disease with as yet unaddressed preventative measures. The hypothesis of this study was that vaccination will prevent clinical and sub-clinical disease. Weanling Thoroughbreds (n= 202) from Central Kentucky were randomly assigned into two groups (vaccinated and non-vaccinated). Vaccinated foals received 30. mL of an avirulent, live L. intracellularis vaccine intra-rectally twice, 30. days apart. Foals were monitored for clinical disease, total solids and average weight gain until yearling age. There was an overall decreased disease incidence on the farms involved in the study that did not differ significantly between the groups. This decreased disease prevalence in the study population may be associated with the ongoing vaccine trial on these farms, as disease prevalence in Central Kentucky did not change in 2009 compared to 2008.

Original languageEnglish (US)
Pages (from-to)511-513
Number of pages3
JournalVeterinary Journal
Volume192
Issue number3
DOIs
StatePublished - Jun 2012

Fingerprint

Lawsonia Bacteria
Lawsonia intracellularis
disease prevalence
foals
Vaccines
vaccines
farms
emerging diseases
total solids
digestive system diseases
weanlings
yearlings
disease incidence
vaccination
weight gain
horses
Horses
Weight Gain
Vaccination
Cross-Sectional Studies

Keywords

  • Daily body weight gain
  • Equine proliferative enteropathy
  • Hypoproteinemia
  • Lawsonia intracellularis
  • Vaccine efficacy

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

Cite this

Nogradi, N., Slovis, N. M., Gebhart, C. J., Wolfsdorf, K. E., McCracken, J. L., Scoggin, C. F., ... Pusterla, N. (2012). Evaluation of the field efficacy of an avirulent live Lawsonia intracellularis vaccine in foals. Veterinary Journal, 192(3), 511-513. https://doi.org/10.1016/j.tvjl.2011.05.026

Evaluation of the field efficacy of an avirulent live Lawsonia intracellularis vaccine in foals. / Nogradi, N.; Slovis, N. M.; Gebhart, C. J.; Wolfsdorf, K. E.; McCracken, J. L.; Scoggin, C. F.; Kass, Philip H; Mapes, S. M.; Toth, B.; Lundquist, M. L.; Pusterla, Nicola.

In: Veterinary Journal, Vol. 192, No. 3, 06.2012, p. 511-513.

Research output: Contribution to journalArticle

Nogradi, N, Slovis, NM, Gebhart, CJ, Wolfsdorf, KE, McCracken, JL, Scoggin, CF, Kass, PH, Mapes, SM, Toth, B, Lundquist, ML & Pusterla, N 2012, 'Evaluation of the field efficacy of an avirulent live Lawsonia intracellularis vaccine in foals', Veterinary Journal, vol. 192, no. 3, pp. 511-513. https://doi.org/10.1016/j.tvjl.2011.05.026
Nogradi N, Slovis NM, Gebhart CJ, Wolfsdorf KE, McCracken JL, Scoggin CF et al. Evaluation of the field efficacy of an avirulent live Lawsonia intracellularis vaccine in foals. Veterinary Journal. 2012 Jun;192(3):511-513. https://doi.org/10.1016/j.tvjl.2011.05.026
Nogradi, N. ; Slovis, N. M. ; Gebhart, C. J. ; Wolfsdorf, K. E. ; McCracken, J. L. ; Scoggin, C. F. ; Kass, Philip H ; Mapes, S. M. ; Toth, B. ; Lundquist, M. L. ; Pusterla, Nicola. / Evaluation of the field efficacy of an avirulent live Lawsonia intracellularis vaccine in foals. In: Veterinary Journal. 2012 ; Vol. 192, No. 3. pp. 511-513.
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