Evaluation of the antibody response in pigs vaccinated against Streptococcus suis capsular type 2 using a Double-antibody sandwich Enzyme-linked immunosorbent assay

C. Blouin, Robert Higgins, M. Gottschalk, J. Simard

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

A double-antibody sandwich enzyme-linked immunosorbent assay (ELISA) was standardized for the detection of specific antibodies following vaccination with Streptococcus suis capsular type 2 bacterins. No statistically significant increase of antibody titers was detected in vaccinated piglets compared to the non-vaccinated control group, even if a minority of piglets demonstrated an important postvaccinal response. Three of four vaccinated sows showed a low antibody response to vaccine and specific immunity was detected in piglets of only one litter of these three sows. Passive protection studies showed that none of the sera from vaccinated piglets were protective for mice whereas serum obtained from hyperimmunized pigs gave protection.

Original languageEnglish (US)
Pages (from-to)49-54
Number of pages6
JournalCanadian Journal of Veterinary Research
Volume58
Issue number1
StatePublished - Jan 1 1994
Externally publishedYes

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Streptococcus suis
Antibody Formation
piglets
Swine
Enzyme-Linked Immunosorbent Assay
enzyme-linked immunosorbent assay
swine
antibodies
Antibodies
Bacterial Vaccines
sows
Serum
Immunity
Vaccination
Vaccines
litters (young animals)
Control Groups
immunity
vaccination
vaccines

Keywords

  • Dr.

ASJC Scopus subject areas

  • veterinary(all)

Cite this

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