Abstract
A double-antibody sandwich enzyme-linked immunosorbent assay (ELISA) was standardized for the detection of specific antibodies following vaccination with Streptococcus suis capsular type 2 bacterins. No statistically significant increase of antibody titers was detected in vaccinated piglets compared to the non-vaccinated control group, even if a minority of piglets demonstrated an important postvaccinal response. Three of four vaccinated sows showed a low antibody response to vaccine and specific immunity was detected in piglets of only one litter of these three sows. Passive protection studies showed that none of the sera from vaccinated piglets were protective for mice whereas serum obtained from hyperimmunized pigs gave protection.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 49-54 |
| Number of pages | 6 |
| Journal | Canadian Journal of Veterinary Research |
| Volume | 58 |
| Issue number | 1 |
| State | Published - Jan 1 1994 |
| Externally published | Yes |
Fingerprint
Keywords
- Dr.
ASJC Scopus subject areas
- veterinary(all)
Cite this
Evaluation of the antibody response in pigs vaccinated against Streptococcus suis capsular type 2 using a Double-antibody sandwich Enzyme-linked immunosorbent assay. / Blouin, C.; Higgins, Robert; Gottschalk, M.; Simard, J.
In: Canadian Journal of Veterinary Research, Vol. 58, No. 1, 01.01.1994, p. 49-54.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Evaluation of the antibody response in pigs vaccinated against Streptococcus suis capsular type 2 using a Double-antibody sandwich Enzyme-linked immunosorbent assay
AU - Blouin, C.
AU - Higgins, Robert
AU - Gottschalk, M.
AU - Simard, J.
PY - 1994/1/1
Y1 - 1994/1/1
N2 - A double-antibody sandwich enzyme-linked immunosorbent assay (ELISA) was standardized for the detection of specific antibodies following vaccination with Streptococcus suis capsular type 2 bacterins. No statistically significant increase of antibody titers was detected in vaccinated piglets compared to the non-vaccinated control group, even if a minority of piglets demonstrated an important postvaccinal response. Three of four vaccinated sows showed a low antibody response to vaccine and specific immunity was detected in piglets of only one litter of these three sows. Passive protection studies showed that none of the sera from vaccinated piglets were protective for mice whereas serum obtained from hyperimmunized pigs gave protection.
AB - A double-antibody sandwich enzyme-linked immunosorbent assay (ELISA) was standardized for the detection of specific antibodies following vaccination with Streptococcus suis capsular type 2 bacterins. No statistically significant increase of antibody titers was detected in vaccinated piglets compared to the non-vaccinated control group, even if a minority of piglets demonstrated an important postvaccinal response. Three of four vaccinated sows showed a low antibody response to vaccine and specific immunity was detected in piglets of only one litter of these three sows. Passive protection studies showed that none of the sera from vaccinated piglets were protective for mice whereas serum obtained from hyperimmunized pigs gave protection.
KW - Dr.
UR - http://www.scopus.com/inward/record.url?scp=0028266375&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0028266375&partnerID=8YFLogxK
M3 - Article
C2 - 8143253
AN - SCOPUS:0028266375
VL - 58
SP - 49
EP - 54
JO - Canadian Journal of Veterinary Research
JF - Canadian Journal of Veterinary Research
SN - 0830-9000
IS - 1
ER -