Evaluation of a commercial bovine colostrum replacer for achieving passive transfer of immunity in springbok calves (Antidorcas Marsupialis)

Kimberly A. Thompson, Nadine Lamberski, Philip H Kass, David Coons, Munashe Chigerwe

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Failure of passive transfer (FPT) occurs in ruminant species when there is inadequate absorption of immunoglobulins from the colostrum. In zoologic establishments, FPT can be a common occurrence in hand-raised ruminant neonates fed insufficient amounts of colostrum replacer (CR) and/or poor-quality CR. The goals of this study were to investigate the efficacy of a commercial bovine CR at achieving adequate passive transfer of immunity and evaluate tests to assess FPT in nondomestic ruminant species. In the past several years, research in dairy calves has shown that passive transfer rates can be dramatically improved if the CR dose is doubled. The treatment group (n = 10) consisted of springbok (Antidorcas marsupialis) calves fed Land O'Lakes bovine commercial CR at a dose of ≥4.68 g of immunoglobulin G (22 g of CR powder) per kilogram of animal's body weight divided into five feedings over 24 hr. The control group (n = 7) consisted of calves that nursed from their dams. This study reported no significant difference between the proportion of calves with adequate passive transfer in the treatment (80%) and control (71%) groups (P = 1.00). Morbidity and mortality rates until weaning were 0% in both groups. The study also determined the sensitivity and specificity values (n = 37) for five serum tests (γ-glutamyl-transferase [GGT], globulin, glutaraldehyde coagulation [GC], sodium sulfite turbidity test, and total protein) used to determine passive transfer status in springbok calves. This study recommends the following serum tests and cutoff ranges for determining FPT in springbok calves: globulin ≤ 1.85 mg/dl, GGT ≤ 228.5 IU/L, and GC ≥ 28 min.

Original languageEnglish (US)
Pages (from-to)541-548
Number of pages8
JournalJournal of Zoo and Wildlife Medicine
Volume44
Issue number3
DOIs
StatePublished - Sep 2013

Fingerprint

Antidorcas marsupialis
cow colostrum
Colostrum
Passive Immunization
colostrum
immunity
calves
Ruminants
ruminants
glutaraldehyde
coagulation
globulins
Globulins
Glutaral
testing
sodium sulfite
dams (hydrology)
dairy calves
immunoglobulin G
Control Groups

Keywords

  • Antidorcas marsupialis
  • Colostrum
  • Immunoglobulin
  • Passive transfer
  • Ruminant
  • Springbok

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

Cite this

Evaluation of a commercial bovine colostrum replacer for achieving passive transfer of immunity in springbok calves (Antidorcas Marsupialis). / Thompson, Kimberly A.; Lamberski, Nadine; Kass, Philip H; Coons, David; Chigerwe, Munashe.

In: Journal of Zoo and Wildlife Medicine, Vol. 44, No. 3, 09.2013, p. 541-548.

Research output: Contribution to journalArticle

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