Euthanization methods influence cytokine mRNA expression levels in age 0 year Oncorhynchus mykiss

L. Bowen, J. D. Kiernan, K. Eder, I. Werner, C. M. Leutenegger, M. A. Adkison, Ronald Hedrick, M. L. Johnson

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Significant differences in cytokine transcription were found between Oncorhynchus mykiss euthanized using the pharmacological agents MS-222 v. benzocaine and also when contrasting death induced by carbon dioxide asphyxiation v. physical methods (cervical dislocation). This study highlights the need to consider the potentially confounding effect of euthanization method on gene expression data.

Original languageEnglish (US)
Pages (from-to)539-545
Number of pages7
JournalJournal of Fish Biology
Volume79
Issue number2
DOIs
StatePublished - Aug 1 2011

Keywords

  • Benzocaine
  • Carbon dioxide asphyxiation
  • Gene transcription
  • MS-222
  • Salmonid

ASJC Scopus subject areas

  • Aquatic Science
  • Ecology, Evolution, Behavior and Systematics

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    Bowen, L., Kiernan, J. D., Eder, K., Werner, I., Leutenegger, C. M., Adkison, M. A., Hedrick, R., & Johnson, M. L. (2011). Euthanization methods influence cytokine mRNA expression levels in age 0 year Oncorhynchus mykiss. Journal of Fish Biology, 79(2), 539-545. https://doi.org/10.1111/j.1095-8649.2011.03034.x