TRANSCRIPTION is the process that occurs in all organisms whereby the genetic information coded by the nucleotide sequences of DNA is transferred into RNA. This process is initiated by attachment of RNA polymerase to a region of the DNA called the promoter1. Considerable information has accumulated recently concerning the structure and function of prokaryotic promoters, but little insight has been gained into the characteristics of eukaryotic promoters. We report here on experiments that use an E. coli plasmid with an attenuated promoter as a probe for possible eukaryotic promoters.
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