Abstract
This chapter presents an overview of the ethical principles that are essential for the proper conduct, and the continuing progress, of animal research aimed at understanding human disease. The chapter identifies fundamental principles of animal research ethics, and discusses ethical and empirical foundations of these principles. Guidelines are offered for the application of these principles in the design and implementation of animal research projects. The chapter highlights several important ethical issues regarding which the biomedical research community has expressed lack of clarity or disagreement, and suggests considerations that are relevant for the resolution of these issues. Recommendations are offered for the participation by investigators in ethical discussion of their work, and of biomedical animal research generally. The general themes of the chapter are that investigators play the primary role in assuring the ethical conduct of biomedical animal research, and that a crucial foundation of ethical animal research is sound science.
| Original language | English (US) |
|---|---|
| Title of host publication | Animal Models for the Study of Human Disease |
| Subtitle of host publication | Second Edition |
| Publisher | Elsevier Inc. |
| Pages | 1-44 |
| Number of pages | 44 |
| ISBN (Electronic) | 9780124158948 |
| ISBN (Print) | 9780128094686 |
| DOIs | |
| State | Published - Jun 28 2017 |
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Keywords
- Basic research
- Biomedical animal research ethics
- Ethics
- Harm
- Harm-benefit analysis
- Reduction
- Refinement
- Replacement
ASJC Scopus subject areas
- Medicine(all)
- Immunology and Microbiology(all)
Cite this
Ethics in Biomedical Animal Research : The Key Role of the Investigator. / Tannenbaum, Jerrold.
Animal Models for the Study of Human Disease: Second Edition. Elsevier Inc., 2017. p. 1-44.Research output: Chapter in Book/Report/Conference proceeding › Chapter
}
TY - CHAP
T1 - Ethics in Biomedical Animal Research
T2 - The Key Role of the Investigator
AU - Tannenbaum, Jerrold
PY - 2017/6/28
Y1 - 2017/6/28
N2 - This chapter presents an overview of the ethical principles that are essential for the proper conduct, and the continuing progress, of animal research aimed at understanding human disease. The chapter identifies fundamental principles of animal research ethics, and discusses ethical and empirical foundations of these principles. Guidelines are offered for the application of these principles in the design and implementation of animal research projects. The chapter highlights several important ethical issues regarding which the biomedical research community has expressed lack of clarity or disagreement, and suggests considerations that are relevant for the resolution of these issues. Recommendations are offered for the participation by investigators in ethical discussion of their work, and of biomedical animal research generally. The general themes of the chapter are that investigators play the primary role in assuring the ethical conduct of biomedical animal research, and that a crucial foundation of ethical animal research is sound science.
AB - This chapter presents an overview of the ethical principles that are essential for the proper conduct, and the continuing progress, of animal research aimed at understanding human disease. The chapter identifies fundamental principles of animal research ethics, and discusses ethical and empirical foundations of these principles. Guidelines are offered for the application of these principles in the design and implementation of animal research projects. The chapter highlights several important ethical issues regarding which the biomedical research community has expressed lack of clarity or disagreement, and suggests considerations that are relevant for the resolution of these issues. Recommendations are offered for the participation by investigators in ethical discussion of their work, and of biomedical animal research generally. The general themes of the chapter are that investigators play the primary role in assuring the ethical conduct of biomedical animal research, and that a crucial foundation of ethical animal research is sound science.
KW - Basic research
KW - Biomedical animal research ethics
KW - Ethics
KW - Harm
KW - Harm-benefit analysis
KW - Reduction
KW - Refinement
KW - Replacement
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UR - http://www.scopus.com/inward/citedby.url?scp=85032679427&partnerID=8YFLogxK
U2 - 10.1016/B978-0-12-809468-6.00001-2
DO - 10.1016/B978-0-12-809468-6.00001-2
M3 - Chapter
AN - SCOPUS:85032679427
SN - 9780128094686
SP - 1
EP - 44
BT - Animal Models for the Study of Human Disease
PB - Elsevier Inc.
ER -