Establishment of the hematopoietic microenvironment in the marrow of matrix-induced endochondral bone

K. F. McCarthy, S. Wientroub, M. Hale, A Hari Reddi

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Implantation of demineralized diaphyseal bone matrix (DBM) into subcutaneous sites in allogeneic Long-Evans rats results in new endochondral bone formation accompanied by hematopoietic bone marrow differentiation in the newly formed ossicles. In the present study, we investigated the relationship between the time of appearance of hematopoietic stem cells (CFU-S) and those of certain postulated elements of the hematopoietic microenvironment, i.e., fibroblast colony-forming cells (CFC-F), colony-stimulating factors (CSF), and collagen types.

Original languageEnglish (US)
Pages (from-to)131-138
Number of pages8
JournalExperimental Hematology
Volume12
Issue number2
StatePublished - 1984
Externally publishedYes

Fingerprint

Colony-Stimulating Factors
Long Evans Rats
Bone Matrix
Hematopoietic Stem Cells
Osteogenesis
Collagen
Fibroblasts
Bone Marrow
Bone and Bones

ASJC Scopus subject areas

  • Cancer Research
  • Cell Biology
  • Genetics
  • Hematology
  • Oncology
  • Transplantation

Cite this

Establishment of the hematopoietic microenvironment in the marrow of matrix-induced endochondral bone. / McCarthy, K. F.; Wientroub, S.; Hale, M.; Reddi, A Hari.

In: Experimental Hematology, Vol. 12, No. 2, 1984, p. 131-138.

Research output: Contribution to journalArticle

@article{4e64140c6cda4e00b98252d9174399c1,
title = "Establishment of the hematopoietic microenvironment in the marrow of matrix-induced endochondral bone",
abstract = "Implantation of demineralized diaphyseal bone matrix (DBM) into subcutaneous sites in allogeneic Long-Evans rats results in new endochondral bone formation accompanied by hematopoietic bone marrow differentiation in the newly formed ossicles. In the present study, we investigated the relationship between the time of appearance of hematopoietic stem cells (CFU-S) and those of certain postulated elements of the hematopoietic microenvironment, i.e., fibroblast colony-forming cells (CFC-F), colony-stimulating factors (CSF), and collagen types.",
author = "McCarthy, {K. F.} and S. Wientroub and M. Hale and Reddi, {A Hari}",
year = "1984",
language = "English (US)",
volume = "12",
pages = "131--138",
journal = "Experimental Hematology",
issn = "0301-472X",
publisher = "Elsevier Inc.",
number = "2",

}

TY - JOUR

T1 - Establishment of the hematopoietic microenvironment in the marrow of matrix-induced endochondral bone

AU - McCarthy, K. F.

AU - Wientroub, S.

AU - Hale, M.

AU - Reddi, A Hari

PY - 1984

Y1 - 1984

N2 - Implantation of demineralized diaphyseal bone matrix (DBM) into subcutaneous sites in allogeneic Long-Evans rats results in new endochondral bone formation accompanied by hematopoietic bone marrow differentiation in the newly formed ossicles. In the present study, we investigated the relationship between the time of appearance of hematopoietic stem cells (CFU-S) and those of certain postulated elements of the hematopoietic microenvironment, i.e., fibroblast colony-forming cells (CFC-F), colony-stimulating factors (CSF), and collagen types.

AB - Implantation of demineralized diaphyseal bone matrix (DBM) into subcutaneous sites in allogeneic Long-Evans rats results in new endochondral bone formation accompanied by hematopoietic bone marrow differentiation in the newly formed ossicles. In the present study, we investigated the relationship between the time of appearance of hematopoietic stem cells (CFU-S) and those of certain postulated elements of the hematopoietic microenvironment, i.e., fibroblast colony-forming cells (CFC-F), colony-stimulating factors (CSF), and collagen types.

UR - http://www.scopus.com/inward/record.url?scp=0021140582&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021140582&partnerID=8YFLogxK

M3 - Article

C2 - 6698132

AN - SCOPUS:0021140582

VL - 12

SP - 131

EP - 138

JO - Experimental Hematology

JF - Experimental Hematology

SN - 0301-472X

IS - 2

ER -