Establishment of equine T-lymphocyte cultures dependent on recombinant human interleukin-2.

M. L. Stott, Bennie Osburn

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

Long-term equine lymphocyte cultures were initiated and maintained in continuous culture with medium containing recombinant human interleukin-2. Cultures were successfully maintained with lectin activation signals and recombinant human interleukin-2 or with recombinant human interleukin-2 alone. All cell cultures that were characterized had a T-lymphocyte phenotype and had lectin-dependent or -independent cytotoxicity directed to various cell types. These findings demonstrate that long-term equine T-lymphocytes cultures can be initiated and maintained easily.

Original languageEnglish (US)
Pages (from-to)553-556
Number of pages4
JournalAmerican Journal of Veterinary Research
Volume49
Issue number4
StatePublished - Apr 1 1988

ASJC Scopus subject areas

  • veterinary(all)

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