Errors in measurement and reporting of serum markers in patients with germ cell tumors

Fredric M. Kardon; John G. Krikorian; JoséA Lopez; Ralph W deVere White

doi:10.1016/0090-4295(82)90116-9

Errors in measurement and reporting of serum markers in patients with germ cell tumors

Fredric M. Kardon, John G. Krikorian, JoséA Lopez, Ralph W deVere White

Research output: Contribution to journal › Article

5 Scopus citations

Abstract

Elevation of the serum value of either human chorionic gonadotropin or alpha-fetoprotein in patients with germ cell testicular tumors is often accepted as evidence for persistent malignancy in the absence of histologic confirmation. These laboratory values are not subject to review and confirmation, unlike histologic diagnosis. We report 3 cases in which serum marker values were incorrectly reported to be elevated by commercial laboratories over a thirteen-month period and suggest a method for handling serum samples to avoid errors in diagnosis.

Original language	English (US)
Pages (from-to)	476-478
Number of pages	3
Journal	Urology
Volume	20
Issue number	5
DOIs	https://doi.org/10.1016/0090-4295(82)90116-9
State	Published - 1982
Externally published	Yes

ASJC Scopus subject areas

Urology

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title = "Errors in measurement and reporting of serum markers in patients with germ cell tumors",

abstract = "Elevation of the serum value of either human chorionic gonadotropin or alpha-fetoprotein in patients with germ cell testicular tumors is often accepted as evidence for persistent malignancy in the absence of histologic confirmation. These laboratory values are not subject to review and confirmation, unlike histologic diagnosis. We report 3 cases in which serum marker values were incorrectly reported to be elevated by commercial laboratories over a thirteen-month period and suggest a method for handling serum samples to avoid errors in diagnosis.",

author = "Kardon, {Fredric M.} and Krikorian, {John G.} and Jos{\'e}A Lopez and {deVere White}, {Ralph W}",

year = "1982",

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AU - Kardon, Fredric M.

AU - Krikorian, John G.

AU - Lopez, JoséA

AU - deVere White, Ralph W

PY - 1982

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AB - Elevation of the serum value of either human chorionic gonadotropin or alpha-fetoprotein in patients with germ cell testicular tumors is often accepted as evidence for persistent malignancy in the absence of histologic confirmation. These laboratory values are not subject to review and confirmation, unlike histologic diagnosis. We report 3 cases in which serum marker values were incorrectly reported to be elevated by commercial laboratories over a thirteen-month period and suggest a method for handling serum samples to avoid errors in diagnosis.

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