ERP and fMRI measures of visual spatial selective attention

George R Mangun, Michael H. Buonocore, Massimo Girelli, Amishi P. Jha

Research output: Contribution to journalArticle

166 Citations (Scopus)

Abstract

In two prior studies, we investigated the neural mechanisms of spatial attention using a combined event-related potential (ERP) and positron emission tomography (PET) approach (Heinze et al. [1994]: Nature 392:543- 546; Mangun et al. [1997]: Hum Brain Mapp 5:273-279). Neural activations in extrastriate cortex were observed in the PET measures for attended stimuli, and these effects were related to attentional modulations in the ERPs at specific latencies. The present study used functional magnetic resonance imaging (fMRI) and ERPs in single subjects to investigate the intersubject variability in extrastriate spatial attention effects, and to qualitatively compare this to variations in ERP attention effects. Activations in single subjects replicated our prior group-averaged PET findings, showing attention- related increases in blood flow in the posterior fusiform and middle occipital gyri in the hemisphere contralateral to attended visual stimuli. All subjects showed attentional modulations of the occipital P1 component of the ERPs. These findings in single subjects demonstrate the consistency of extrastriate attention effects, and provide information about the feasibility of this approach for integration of electrical and functional imaging data.

Original languageEnglish (US)
Pages (from-to)383-389
Number of pages7
JournalHuman Brain Mapping
Volume6
Issue number5-6
DOIs
StatePublished - 1998

Fingerprint

Evoked Potentials
Positron-Emission Tomography
Magnetic Resonance Imaging
Occipital Lobe
Visual Cortex
Brain

Keywords

  • ERP
  • fMRI
  • Spatial attention
  • Visual stimuli

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)
  • Radiological and Ultrasound Technology

Cite this

ERP and fMRI measures of visual spatial selective attention. / Mangun, George R; Buonocore, Michael H.; Girelli, Massimo; Jha, Amishi P.

In: Human Brain Mapping, Vol. 6, No. 5-6, 1998, p. 383-389.

Research output: Contribution to journalArticle

Mangun, George R ; Buonocore, Michael H. ; Girelli, Massimo ; Jha, Amishi P. / ERP and fMRI measures of visual spatial selective attention. In: Human Brain Mapping. 1998 ; Vol. 6, No. 5-6. pp. 383-389.
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