Equine proliferative enteropathy - a review of recent developments

Nicola Pusterla, C. J. Gebhart

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Equine proliferative enteropathy (EPE) is a disease of foals caused by the obligate intracellular organism Lawsonia intracellularis. This emerging disease affects mainly weanling foals and causes fever, lethargy, peripheral oedema, diarrhoea, colic and weight loss. The diagnosis of EPE may be challenging and relies on the presence of hypoproteinaemia, thickening of segments of the small intestinal wall observed upon abdominal ultrasonography, positive serology and molecular detection of L.intracellularis in faeces. Although the clinical entity, diagnostic approach and treatment of EPE are well established and described, the epidemiology for this disease has remained largely unaddressed. This article focuses on new developments in the field of EPE, including epidemiology, pathophysiology, clinical signs, diagnosis, treatment and prevention.

Original languageEnglish (US)
Pages (from-to)403-409
Number of pages7
JournalEquine Veterinary Journal
Volume45
Issue number4
DOIs
StatePublished - Jul 2013

Fingerprint

digestive system diseases
Horses
horses
foals
epidemiology
Lawsonia Bacteria
Epidemiology
Hypoproteinemia
Lawsonia intracellularis
Lethargy
Colic
emerging diseases
colic
Serology
pathophysiology
weanlings
Feces
ultrasonography
edema
fever

Keywords

  • Clinical management
  • Equine proliferative enteropathy
  • Horse
  • Lawsonia intracellularis
  • Pathophysiology

ASJC Scopus subject areas

  • Equine

Cite this

Equine proliferative enteropathy - a review of recent developments. / Pusterla, Nicola; Gebhart, C. J.

In: Equine Veterinary Journal, Vol. 45, No. 4, 07.2013, p. 403-409.

Research output: Contribution to journalArticle

@article{89c138b431104c2388211a680b7867d7,
title = "Equine proliferative enteropathy - a review of recent developments",
abstract = "Equine proliferative enteropathy (EPE) is a disease of foals caused by the obligate intracellular organism Lawsonia intracellularis. This emerging disease affects mainly weanling foals and causes fever, lethargy, peripheral oedema, diarrhoea, colic and weight loss. The diagnosis of EPE may be challenging and relies on the presence of hypoproteinaemia, thickening of segments of the small intestinal wall observed upon abdominal ultrasonography, positive serology and molecular detection of L.intracellularis in faeces. Although the clinical entity, diagnostic approach and treatment of EPE are well established and described, the epidemiology for this disease has remained largely unaddressed. This article focuses on new developments in the field of EPE, including epidemiology, pathophysiology, clinical signs, diagnosis, treatment and prevention.",
keywords = "Clinical management, Equine proliferative enteropathy, Horse, Lawsonia intracellularis, Pathophysiology",
author = "Nicola Pusterla and Gebhart, {C. J.}",
year = "2013",
month = "7",
doi = "10.1111/evj.12075",
language = "English (US)",
volume = "45",
pages = "403--409",
journal = "Equine veterinary journal. Supplement",
issn = "2042-3306",
publisher = "British Equine Veterinary Association",
number = "4",

}

TY - JOUR

T1 - Equine proliferative enteropathy - a review of recent developments

AU - Pusterla, Nicola

AU - Gebhart, C. J.

PY - 2013/7

Y1 - 2013/7

N2 - Equine proliferative enteropathy (EPE) is a disease of foals caused by the obligate intracellular organism Lawsonia intracellularis. This emerging disease affects mainly weanling foals and causes fever, lethargy, peripheral oedema, diarrhoea, colic and weight loss. The diagnosis of EPE may be challenging and relies on the presence of hypoproteinaemia, thickening of segments of the small intestinal wall observed upon abdominal ultrasonography, positive serology and molecular detection of L.intracellularis in faeces. Although the clinical entity, diagnostic approach and treatment of EPE are well established and described, the epidemiology for this disease has remained largely unaddressed. This article focuses on new developments in the field of EPE, including epidemiology, pathophysiology, clinical signs, diagnosis, treatment and prevention.

AB - Equine proliferative enteropathy (EPE) is a disease of foals caused by the obligate intracellular organism Lawsonia intracellularis. This emerging disease affects mainly weanling foals and causes fever, lethargy, peripheral oedema, diarrhoea, colic and weight loss. The diagnosis of EPE may be challenging and relies on the presence of hypoproteinaemia, thickening of segments of the small intestinal wall observed upon abdominal ultrasonography, positive serology and molecular detection of L.intracellularis in faeces. Although the clinical entity, diagnostic approach and treatment of EPE are well established and described, the epidemiology for this disease has remained largely unaddressed. This article focuses on new developments in the field of EPE, including epidemiology, pathophysiology, clinical signs, diagnosis, treatment and prevention.

KW - Clinical management

KW - Equine proliferative enteropathy

KW - Horse

KW - Lawsonia intracellularis

KW - Pathophysiology

UR - http://www.scopus.com/inward/record.url?scp=84878928626&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84878928626&partnerID=8YFLogxK

U2 - 10.1111/evj.12075

DO - 10.1111/evj.12075

M3 - Article

C2 - 23662705

AN - SCOPUS:84878928626

VL - 45

SP - 403

EP - 409

JO - Equine veterinary journal. Supplement

JF - Equine veterinary journal. Supplement

SN - 2042-3306

IS - 4

ER -