Equine papillary ependymoma

M. J. Carrigan, R. J. Higgins, G. P. Carlson, D. K. Naydan

Research output: Contribution to journalArticlepeer-review

26 Scopus citations


A 17-year-old Arabian gelding with progressive neurologic signs had a velvety, reddish brain tumor protruding from the ventral midline caudal to the optic chiasma. Histologically, the tumor had a papillary formation with a single layer of elongate cells radially oriented around a central fibrovascular core. Intracytoplasmic globular inclusions were positive for glial fibrillary acidic protein and weakly positive for vimentin. Ultrastructurally, these inclusions were comprised of whorling intermediate filaments. Neoplastic cells also had cytoplasmic interdigitations and numerous zona adherens and often rested on a basal lamina. The tumor was diagnosed as a papillary ependymoma.

Original languageEnglish (US)
Pages (from-to)77-80
Number of pages4
JournalVeterinary Pathology
Issue number1
StatePublished - Jan 1 1996


  • Central nervous system
  • Equine
  • Horses
  • Immunocytochemistry
  • Papillary ependymoma
  • Ultrastructure

ASJC Scopus subject areas

  • veterinary(all)


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