Equine Influenza Virus

Christine Myers, William D Wilson

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Equine influenza virus is a highly contagious agent that is capable of causing explosive outbreaks of respiratory disease among susceptible horse populations. The virus infects the mucosal cells of the upper and lower respiratory tract, and induces respiratory disease characterized by a harsh dry cough and fever. Infection is generally self-limiting and the majority of horses recover uneventfully; however, the recovery period may take several weeks to months. Outbreaks affecting performance horses exert a significant economic impact on the equine industry due to loss of performance and time out of work. Vaccination and careful management can limit the spread and severity of disease among groups of horses, but, in the past, vaccines have often failed to provide adequate protection. Vaccine failure has been attributed to genetic and antigenic drift of the influenza A/equine/2 virus from vaccine strains, as well as failure of some vaccines to stimulate the appropriate array of immune responses. This article offers the equine veterinarian a practical approach to preventing infection and the steps that can be taken to promote rapid diagnosis and effective control of outbreaks if preventive measures fail. Epidemiology, pathophysiology, clinical presentation, treatment, vaccines, and vaccination protocols are discussed, and a brief discussion of future technologies is presented.

Original languageEnglish (US)
Pages (from-to)187-196
Number of pages10
JournalClinical Techniques in Equine Practice
Volume5
Issue number3
DOIs
StatePublished - Sep 2006

Fingerprint

Orthomyxoviridae
Influenza A virus
Horses
horses
vaccines
Vaccines
Disease Outbreaks
respiratory tract diseases
vaccination
Vaccination
antigenic variation
viruses
Viruses
cough
Genetic Drift
genetic drift
economic impact
pathophysiology
Veterinarians
respiratory system

Keywords

  • equine influenza virus
  • prevention
  • vaccination

ASJC Scopus subject areas

  • Equine

Cite this

Equine Influenza Virus. / Myers, Christine; Wilson, William D.

In: Clinical Techniques in Equine Practice, Vol. 5, No. 3, 09.2006, p. 187-196.

Research output: Contribution to journalArticle

Myers, Christine ; Wilson, William D. / Equine Influenza Virus. In: Clinical Techniques in Equine Practice. 2006 ; Vol. 5, No. 3. pp. 187-196.
@article{be3c2108ee964a27b840e6aa2a5994ce,
title = "Equine Influenza Virus",
abstract = "Equine influenza virus is a highly contagious agent that is capable of causing explosive outbreaks of respiratory disease among susceptible horse populations. The virus infects the mucosal cells of the upper and lower respiratory tract, and induces respiratory disease characterized by a harsh dry cough and fever. Infection is generally self-limiting and the majority of horses recover uneventfully; however, the recovery period may take several weeks to months. Outbreaks affecting performance horses exert a significant economic impact on the equine industry due to loss of performance and time out of work. Vaccination and careful management can limit the spread and severity of disease among groups of horses, but, in the past, vaccines have often failed to provide adequate protection. Vaccine failure has been attributed to genetic and antigenic drift of the influenza A/equine/2 virus from vaccine strains, as well as failure of some vaccines to stimulate the appropriate array of immune responses. This article offers the equine veterinarian a practical approach to preventing infection and the steps that can be taken to promote rapid diagnosis and effective control of outbreaks if preventive measures fail. Epidemiology, pathophysiology, clinical presentation, treatment, vaccines, and vaccination protocols are discussed, and a brief discussion of future technologies is presented.",
keywords = "equine influenza virus, prevention, vaccination",
author = "Christine Myers and Wilson, {William D}",
year = "2006",
month = "9",
doi = "10.1053/j.ctep.2006.03.013",
language = "English (US)",
volume = "5",
pages = "187--196",
journal = "Clinical Techniques in Equine Practice",
issn = "1534-7516",
publisher = "W.B. Saunders Ltd",
number = "3",

}

TY - JOUR

T1 - Equine Influenza Virus

AU - Myers, Christine

AU - Wilson, William D

PY - 2006/9

Y1 - 2006/9

N2 - Equine influenza virus is a highly contagious agent that is capable of causing explosive outbreaks of respiratory disease among susceptible horse populations. The virus infects the mucosal cells of the upper and lower respiratory tract, and induces respiratory disease characterized by a harsh dry cough and fever. Infection is generally self-limiting and the majority of horses recover uneventfully; however, the recovery period may take several weeks to months. Outbreaks affecting performance horses exert a significant economic impact on the equine industry due to loss of performance and time out of work. Vaccination and careful management can limit the spread and severity of disease among groups of horses, but, in the past, vaccines have often failed to provide adequate protection. Vaccine failure has been attributed to genetic and antigenic drift of the influenza A/equine/2 virus from vaccine strains, as well as failure of some vaccines to stimulate the appropriate array of immune responses. This article offers the equine veterinarian a practical approach to preventing infection and the steps that can be taken to promote rapid diagnosis and effective control of outbreaks if preventive measures fail. Epidemiology, pathophysiology, clinical presentation, treatment, vaccines, and vaccination protocols are discussed, and a brief discussion of future technologies is presented.

AB - Equine influenza virus is a highly contagious agent that is capable of causing explosive outbreaks of respiratory disease among susceptible horse populations. The virus infects the mucosal cells of the upper and lower respiratory tract, and induces respiratory disease characterized by a harsh dry cough and fever. Infection is generally self-limiting and the majority of horses recover uneventfully; however, the recovery period may take several weeks to months. Outbreaks affecting performance horses exert a significant economic impact on the equine industry due to loss of performance and time out of work. Vaccination and careful management can limit the spread and severity of disease among groups of horses, but, in the past, vaccines have often failed to provide adequate protection. Vaccine failure has been attributed to genetic and antigenic drift of the influenza A/equine/2 virus from vaccine strains, as well as failure of some vaccines to stimulate the appropriate array of immune responses. This article offers the equine veterinarian a practical approach to preventing infection and the steps that can be taken to promote rapid diagnosis and effective control of outbreaks if preventive measures fail. Epidemiology, pathophysiology, clinical presentation, treatment, vaccines, and vaccination protocols are discussed, and a brief discussion of future technologies is presented.

KW - equine influenza virus

KW - prevention

KW - vaccination

UR - http://www.scopus.com/inward/record.url?scp=33747368290&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33747368290&partnerID=8YFLogxK

U2 - 10.1053/j.ctep.2006.03.013

DO - 10.1053/j.ctep.2006.03.013

M3 - Article

AN - SCOPUS:33747368290

VL - 5

SP - 187

EP - 196

JO - Clinical Techniques in Equine Practice

JF - Clinical Techniques in Equine Practice

SN - 1534-7516

IS - 3

ER -