Abstract
Women who present with pulmonary hypertension during gestation have traditionally been persuaded to terminate their pregnancy. Historically, the mortality associated with this group is very high. Certain patients with a secondary cause of pulmonary hypertension are believed to share similar pathophysiology with primary pulmonary hypertension patients. Recently, new treatments have become available that have slowed disease progression. We present the successful treatment of two patients who presented during late gestation with moderate pulmonary hypertension. Both patients were managed with intravenous vasodilators and anticoagulants without complication. Each patient successfully delivered a healthy child via spontaneous vaginal delivery. The review of the historical management of similar patients including new insights into the etiology of pulmonary arterial hypertension is also included. It highlights the complexity involved in managing such patients and the requirement of a multidisiplinary team approach.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 29-34 |
| Number of pages | 6 |
| Journal | Treatments in Respiratory Medicine |
| Volume | 3 |
| Issue number | 1 |
| DOIs | |
| State | Published - 2004 |
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ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine
Cite this
Epoprostenol in pregnant patients with secondary pulmonary hypertension : Two case reports and a review of the literature. / Avdalovic, Mark V; Sandrock, Christian E; Hoso, Andrea; Allen, Roblee P; Albertson, Timothy E.
In: Treatments in Respiratory Medicine, Vol. 3, No. 1, 2004, p. 29-34.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Epoprostenol in pregnant patients with secondary pulmonary hypertension
T2 - Two case reports and a review of the literature
AU - Avdalovic, Mark V
AU - Sandrock, Christian E
AU - Hoso, Andrea
AU - Allen, Roblee P
AU - Albertson, Timothy E
PY - 2004
Y1 - 2004
N2 - Women who present with pulmonary hypertension during gestation have traditionally been persuaded to terminate their pregnancy. Historically, the mortality associated with this group is very high. Certain patients with a secondary cause of pulmonary hypertension are believed to share similar pathophysiology with primary pulmonary hypertension patients. Recently, new treatments have become available that have slowed disease progression. We present the successful treatment of two patients who presented during late gestation with moderate pulmonary hypertension. Both patients were managed with intravenous vasodilators and anticoagulants without complication. Each patient successfully delivered a healthy child via spontaneous vaginal delivery. The review of the historical management of similar patients including new insights into the etiology of pulmonary arterial hypertension is also included. It highlights the complexity involved in managing such patients and the requirement of a multidisiplinary team approach.
AB - Women who present with pulmonary hypertension during gestation have traditionally been persuaded to terminate their pregnancy. Historically, the mortality associated with this group is very high. Certain patients with a secondary cause of pulmonary hypertension are believed to share similar pathophysiology with primary pulmonary hypertension patients. Recently, new treatments have become available that have slowed disease progression. We present the successful treatment of two patients who presented during late gestation with moderate pulmonary hypertension. Both patients were managed with intravenous vasodilators and anticoagulants without complication. Each patient successfully delivered a healthy child via spontaneous vaginal delivery. The review of the historical management of similar patients including new insights into the etiology of pulmonary arterial hypertension is also included. It highlights the complexity involved in managing such patients and the requirement of a multidisiplinary team approach.
UR - http://www.scopus.com/inward/record.url?scp=1842608806&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=1842608806&partnerID=8YFLogxK
U2 - 10.2165/00151829-200403010-00004
DO - 10.2165/00151829-200403010-00004
M3 - Article
C2 - 15174891
AN - SCOPUS:1842608806
VL - 3
SP - 29
EP - 34
JO - Treatments in Respiratory Medicine
JF - Treatments in Respiratory Medicine
SN - 1176-3450
IS - 1
ER -