Abstract
Objective - To determine whether breed, sex, country of origin, and age are associated with anatomic location of intrahepatic portosystemic shunts (IHPSS) in dogs. Study Design - Multi-institutional retrospective case series. Sample Population - Dogs (n=125) with IHPSS from the veterinary teaching hospitals of the University of Florida (21), Sydney University (44), and the University of California - Davis (60). Methods - Dogs with surgical/necropsy confirmation of single IHPSS were identified. Data were analyzed using logistic regression for associations between age, breed, sex, and country with the anatomic location of IHPSS. Results - Right (34%), left (34%), and central divisional IHPSS (32%) were prevalent with approximately equal frequency in Australia; in the United States, the prevalence of right (24%) and central divisional (26%) combined was similar to left divisional IHPSS (51%). Country (P=048), sex (P=.016), and Australian cattle dog ([ACD], P=.025) were significantly associated with IHPSS location. Dogs in Australia had 2.5-fold higher odds of having right versus left divisional IHPSS. Males and ACD had 2.8- and 5.6-fold higher odds of having right versus left divisional IHPSS. Australian dogs were significantly older than those in the United States (P<.0001) and ACD were significantly older than other breeds (P=.0067). Conclusions - Although country of origin, breed, and sex had significant associations with anatomic location of IHPSS, signalment does not appear to be a strong predictor of shunt location when used alone. Clinical Relevance - For the common breeds in this report, signalment is only occasionally helpful in predicting likelihood of anatomic division in IHPSS. Australian cattle dogs and male dogs have a statistical association with right (versus left) divisional IHPSS. If advanced imaging techniques are not available, veterinary surgeons should be prepared to locate and address any anatomic configuration of IHPSS in a dog.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 31-36 |
| Number of pages | 6 |
| Journal | Veterinary Surgery |
| Volume | 36 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 2007 |
| Externally published | Yes |
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Cite this
Epidemiologic factors associated with the anatomic location of intrahepatic portosystemic shunts in dogs. / Krotscheck, Ursula; Adin, Christopher A.; Hunt, Geraldine B; Kyles, Andrew E.; Erb, Hollis N.
In: Veterinary Surgery, Vol. 36, No. 1, 01.2007, p. 31-36.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Epidemiologic factors associated with the anatomic location of intrahepatic portosystemic shunts in dogs
AU - Krotscheck, Ursula
AU - Adin, Christopher A.
AU - Hunt, Geraldine B
AU - Kyles, Andrew E.
AU - Erb, Hollis N.
PY - 2007/1
Y1 - 2007/1
N2 - Objective - To determine whether breed, sex, country of origin, and age are associated with anatomic location of intrahepatic portosystemic shunts (IHPSS) in dogs. Study Design - Multi-institutional retrospective case series. Sample Population - Dogs (n=125) with IHPSS from the veterinary teaching hospitals of the University of Florida (21), Sydney University (44), and the University of California - Davis (60). Methods - Dogs with surgical/necropsy confirmation of single IHPSS were identified. Data were analyzed using logistic regression for associations between age, breed, sex, and country with the anatomic location of IHPSS. Results - Right (34%), left (34%), and central divisional IHPSS (32%) were prevalent with approximately equal frequency in Australia; in the United States, the prevalence of right (24%) and central divisional (26%) combined was similar to left divisional IHPSS (51%). Country (P=048), sex (P=.016), and Australian cattle dog ([ACD], P=.025) were significantly associated with IHPSS location. Dogs in Australia had 2.5-fold higher odds of having right versus left divisional IHPSS. Males and ACD had 2.8- and 5.6-fold higher odds of having right versus left divisional IHPSS. Australian dogs were significantly older than those in the United States (P<.0001) and ACD were significantly older than other breeds (P=.0067). Conclusions - Although country of origin, breed, and sex had significant associations with anatomic location of IHPSS, signalment does not appear to be a strong predictor of shunt location when used alone. Clinical Relevance - For the common breeds in this report, signalment is only occasionally helpful in predicting likelihood of anatomic division in IHPSS. Australian cattle dogs and male dogs have a statistical association with right (versus left) divisional IHPSS. If advanced imaging techniques are not available, veterinary surgeons should be prepared to locate and address any anatomic configuration of IHPSS in a dog.
AB - Objective - To determine whether breed, sex, country of origin, and age are associated with anatomic location of intrahepatic portosystemic shunts (IHPSS) in dogs. Study Design - Multi-institutional retrospective case series. Sample Population - Dogs (n=125) with IHPSS from the veterinary teaching hospitals of the University of Florida (21), Sydney University (44), and the University of California - Davis (60). Methods - Dogs with surgical/necropsy confirmation of single IHPSS were identified. Data were analyzed using logistic regression for associations between age, breed, sex, and country with the anatomic location of IHPSS. Results - Right (34%), left (34%), and central divisional IHPSS (32%) were prevalent with approximately equal frequency in Australia; in the United States, the prevalence of right (24%) and central divisional (26%) combined was similar to left divisional IHPSS (51%). Country (P=048), sex (P=.016), and Australian cattle dog ([ACD], P=.025) were significantly associated with IHPSS location. Dogs in Australia had 2.5-fold higher odds of having right versus left divisional IHPSS. Males and ACD had 2.8- and 5.6-fold higher odds of having right versus left divisional IHPSS. Australian dogs were significantly older than those in the United States (P<.0001) and ACD were significantly older than other breeds (P=.0067). Conclusions - Although country of origin, breed, and sex had significant associations with anatomic location of IHPSS, signalment does not appear to be a strong predictor of shunt location when used alone. Clinical Relevance - For the common breeds in this report, signalment is only occasionally helpful in predicting likelihood of anatomic division in IHPSS. Australian cattle dogs and male dogs have a statistical association with right (versus left) divisional IHPSS. If advanced imaging techniques are not available, veterinary surgeons should be prepared to locate and address any anatomic configuration of IHPSS in a dog.
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UR - http://www.scopus.com/inward/citedby.url?scp=33846083940&partnerID=8YFLogxK
U2 - 10.1111/j.1532-950X.2007.00240.x
DO - 10.1111/j.1532-950X.2007.00240.x
M3 - Article
C2 - 17214817
AN - SCOPUS:33846083940
VL - 36
SP - 31
EP - 36
JO - Veterinary Surgery
JF - Veterinary Surgery
SN - 0161-3499
IS - 1
ER -