Epidemiologic factors associated with the anatomic location of intrahepatic portosystemic shunts in dogs

Ursula Krotscheck, Christopher A. Adin, Geraldine B Hunt, Andrew E. Kyles, Hollis N. Erb

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Objective - To determine whether breed, sex, country of origin, and age are associated with anatomic location of intrahepatic portosystemic shunts (IHPSS) in dogs. Study Design - Multi-institutional retrospective case series. Sample Population - Dogs (n=125) with IHPSS from the veterinary teaching hospitals of the University of Florida (21), Sydney University (44), and the University of California - Davis (60). Methods - Dogs with surgical/necropsy confirmation of single IHPSS were identified. Data were analyzed using logistic regression for associations between age, breed, sex, and country with the anatomic location of IHPSS. Results - Right (34%), left (34%), and central divisional IHPSS (32%) were prevalent with approximately equal frequency in Australia; in the United States, the prevalence of right (24%) and central divisional (26%) combined was similar to left divisional IHPSS (51%). Country (P=048), sex (P=.016), and Australian cattle dog ([ACD], P=.025) were significantly associated with IHPSS location. Dogs in Australia had 2.5-fold higher odds of having right versus left divisional IHPSS. Males and ACD had 2.8- and 5.6-fold higher odds of having right versus left divisional IHPSS. Australian dogs were significantly older than those in the United States (P<.0001) and ACD were significantly older than other breeds (P=.0067). Conclusions - Although country of origin, breed, and sex had significant associations with anatomic location of IHPSS, signalment does not appear to be a strong predictor of shunt location when used alone. Clinical Relevance - For the common breeds in this report, signalment is only occasionally helpful in predicting likelihood of anatomic division in IHPSS. Australian cattle dogs and male dogs have a statistical association with right (versus left) divisional IHPSS. If advanced imaging techniques are not available, veterinary surgeons should be prepared to locate and address any anatomic configuration of IHPSS in a dog.

Original languageEnglish (US)
Pages (from-to)31-36
Number of pages6
JournalVeterinary Surgery
Volume36
Issue number1
DOIs
StatePublished - Jan 2007
Externally publishedYes

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Epidemiologic Factors
Surgical Portasystemic Shunt
Dogs
dogs
breeds
gender
veterinarians
necropsy
experimental design
image analysis
Animal Hospitals
Australian Cattle Dog

ASJC Scopus subject areas

  • veterinary(all)

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Epidemiologic factors associated with the anatomic location of intrahepatic portosystemic shunts in dogs. / Krotscheck, Ursula; Adin, Christopher A.; Hunt, Geraldine B; Kyles, Andrew E.; Erb, Hollis N.

In: Veterinary Surgery, Vol. 36, No. 1, 01.2007, p. 31-36.

Research output: Contribution to journalArticle

Krotscheck, Ursula ; Adin, Christopher A. ; Hunt, Geraldine B ; Kyles, Andrew E. ; Erb, Hollis N. / Epidemiologic factors associated with the anatomic location of intrahepatic portosystemic shunts in dogs. In: Veterinary Surgery. 2007 ; Vol. 36, No. 1. pp. 31-36.
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abstract = "Objective - To determine whether breed, sex, country of origin, and age are associated with anatomic location of intrahepatic portosystemic shunts (IHPSS) in dogs. Study Design - Multi-institutional retrospective case series. Sample Population - Dogs (n=125) with IHPSS from the veterinary teaching hospitals of the University of Florida (21), Sydney University (44), and the University of California - Davis (60). Methods - Dogs with surgical/necropsy confirmation of single IHPSS were identified. Data were analyzed using logistic regression for associations between age, breed, sex, and country with the anatomic location of IHPSS. Results - Right (34{\%}), left (34{\%}), and central divisional IHPSS (32{\%}) were prevalent with approximately equal frequency in Australia; in the United States, the prevalence of right (24{\%}) and central divisional (26{\%}) combined was similar to left divisional IHPSS (51{\%}). Country (P=048), sex (P=.016), and Australian cattle dog ([ACD], P=.025) were significantly associated with IHPSS location. Dogs in Australia had 2.5-fold higher odds of having right versus left divisional IHPSS. Males and ACD had 2.8- and 5.6-fold higher odds of having right versus left divisional IHPSS. Australian dogs were significantly older than those in the United States (P<.0001) and ACD were significantly older than other breeds (P=.0067). Conclusions - Although country of origin, breed, and sex had significant associations with anatomic location of IHPSS, signalment does not appear to be a strong predictor of shunt location when used alone. Clinical Relevance - For the common breeds in this report, signalment is only occasionally helpful in predicting likelihood of anatomic division in IHPSS. Australian cattle dogs and male dogs have a statistical association with right (versus left) divisional IHPSS. If advanced imaging techniques are not available, veterinary surgeons should be prepared to locate and address any anatomic configuration of IHPSS in a dog.",
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