Epidemiologic characteristics and management of polysaccharide storage myopathy in Quarter Horses

Anna M. Firshman, Stephanie J. Valberg, Jeffrey B. Bender, Carrie J Finno

Research output: Contribution to journalArticle

60 Citations (Scopus)

Abstract

Objective - To characterize onset and clinical signs of polysaccharide storage myopathy (PSSM) in a well-defined population of affected Quarter Horses, identify risk factors for PSSM, determine compliance of owners to dietary and exercise recommendations, and evaluate the efficacy of dietary and exercise recommendations. Animals - 40 Quarter Horses with PSSM and 37 unaffected control horses. Procedures - Owners of horses with PSSM completed a retrospective questionnaire concerning their horse's condition. Results - Between horses with PSSM and control horses, no significant differences were found in sex distribution (21 vs 15 females and 16 vs 22 males, respectively), temperament, muscle build, diet, or amount of turnout. In horses with PSSM, signs of muscle stiffness, muscle fasciculations, sweating, exercise intolerance, weakness, muscle wasting, reluctance to move, colic, abnormal gait, recumbency, lameness, and swollen muscles began between the age of 1 day and 14 years (mean age, 4.9 ± 3.5 years). Five horses with PSSM developed acute muscle atrophy. Sixty-three percent (25/40) of owners fed the recommended diet, 55% (22/40) provided regular exercise, and 40% (16/40) followed both dietary and exercise recommendations. Owners of affected horses for which a decrease in severity or frequency of PSSM was not found did not follow the exercise, dietary, or both recommendations. All horses for which both dietary and exercise recommendations were followed had improvement in signs of PSSM. Conclusions and Clinical Relevance - In addition to exertional rhabdomyolysis, signs of PSSM include acute muscle atrophy and gait abnormalities. It appears that PSSM can be managed by following dietary recommendations combined with gradual increases in daily exercise.

Original languageEnglish (US)
Pages (from-to)1319-1327
Number of pages9
JournalAmerican Journal of Veterinary Research
Volume64
Issue number10
DOIs
StatePublished - Oct 1 2003
Externally publishedYes

Fingerprint

Quarter Horse
muscular diseases
Muscular Diseases
Horses
Polysaccharides
polysaccharides
exercise
horses
muscles
Muscles
muscular atrophy
Muscular Atrophy
gait
Gait
rhabdomyolysis
Fasciculation
Diet
sweating
Sex Distribution
temperament

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Epidemiologic characteristics and management of polysaccharide storage myopathy in Quarter Horses. / Firshman, Anna M.; Valberg, Stephanie J.; Bender, Jeffrey B.; Finno, Carrie J.

In: American Journal of Veterinary Research, Vol. 64, No. 10, 01.10.2003, p. 1319-1327.

Research output: Contribution to journalArticle

Firshman, Anna M. ; Valberg, Stephanie J. ; Bender, Jeffrey B. ; Finno, Carrie J. / Epidemiologic characteristics and management of polysaccharide storage myopathy in Quarter Horses. In: American Journal of Veterinary Research. 2003 ; Vol. 64, No. 10. pp. 1319-1327.
@article{3d34d7bbe83b4f60b6e9652bfe24dcfd,
title = "Epidemiologic characteristics and management of polysaccharide storage myopathy in Quarter Horses",
abstract = "Objective - To characterize onset and clinical signs of polysaccharide storage myopathy (PSSM) in a well-defined population of affected Quarter Horses, identify risk factors for PSSM, determine compliance of owners to dietary and exercise recommendations, and evaluate the efficacy of dietary and exercise recommendations. Animals - 40 Quarter Horses with PSSM and 37 unaffected control horses. Procedures - Owners of horses with PSSM completed a retrospective questionnaire concerning their horse's condition. Results - Between horses with PSSM and control horses, no significant differences were found in sex distribution (21 vs 15 females and 16 vs 22 males, respectively), temperament, muscle build, diet, or amount of turnout. In horses with PSSM, signs of muscle stiffness, muscle fasciculations, sweating, exercise intolerance, weakness, muscle wasting, reluctance to move, colic, abnormal gait, recumbency, lameness, and swollen muscles began between the age of 1 day and 14 years (mean age, 4.9 ± 3.5 years). Five horses with PSSM developed acute muscle atrophy. Sixty-three percent (25/40) of owners fed the recommended diet, 55{\%} (22/40) provided regular exercise, and 40{\%} (16/40) followed both dietary and exercise recommendations. Owners of affected horses for which a decrease in severity or frequency of PSSM was not found did not follow the exercise, dietary, or both recommendations. All horses for which both dietary and exercise recommendations were followed had improvement in signs of PSSM. Conclusions and Clinical Relevance - In addition to exertional rhabdomyolysis, signs of PSSM include acute muscle atrophy and gait abnormalities. It appears that PSSM can be managed by following dietary recommendations combined with gradual increases in daily exercise.",
author = "Firshman, {Anna M.} and Valberg, {Stephanie J.} and Bender, {Jeffrey B.} and Finno, {Carrie J}",
year = "2003",
month = "10",
day = "1",
doi = "10.2460/ajvr.2003.64.1319",
language = "English (US)",
volume = "64",
pages = "1319--1327",
journal = "American Journal of Veterinary Research",
issn = "0002-9645",
publisher = "American Veterinary Medical Association",
number = "10",

}

TY - JOUR

T1 - Epidemiologic characteristics and management of polysaccharide storage myopathy in Quarter Horses

AU - Firshman, Anna M.

AU - Valberg, Stephanie J.

AU - Bender, Jeffrey B.

AU - Finno, Carrie J

PY - 2003/10/1

Y1 - 2003/10/1

N2 - Objective - To characterize onset and clinical signs of polysaccharide storage myopathy (PSSM) in a well-defined population of affected Quarter Horses, identify risk factors for PSSM, determine compliance of owners to dietary and exercise recommendations, and evaluate the efficacy of dietary and exercise recommendations. Animals - 40 Quarter Horses with PSSM and 37 unaffected control horses. Procedures - Owners of horses with PSSM completed a retrospective questionnaire concerning their horse's condition. Results - Between horses with PSSM and control horses, no significant differences were found in sex distribution (21 vs 15 females and 16 vs 22 males, respectively), temperament, muscle build, diet, or amount of turnout. In horses with PSSM, signs of muscle stiffness, muscle fasciculations, sweating, exercise intolerance, weakness, muscle wasting, reluctance to move, colic, abnormal gait, recumbency, lameness, and swollen muscles began between the age of 1 day and 14 years (mean age, 4.9 ± 3.5 years). Five horses with PSSM developed acute muscle atrophy. Sixty-three percent (25/40) of owners fed the recommended diet, 55% (22/40) provided regular exercise, and 40% (16/40) followed both dietary and exercise recommendations. Owners of affected horses for which a decrease in severity or frequency of PSSM was not found did not follow the exercise, dietary, or both recommendations. All horses for which both dietary and exercise recommendations were followed had improvement in signs of PSSM. Conclusions and Clinical Relevance - In addition to exertional rhabdomyolysis, signs of PSSM include acute muscle atrophy and gait abnormalities. It appears that PSSM can be managed by following dietary recommendations combined with gradual increases in daily exercise.

AB - Objective - To characterize onset and clinical signs of polysaccharide storage myopathy (PSSM) in a well-defined population of affected Quarter Horses, identify risk factors for PSSM, determine compliance of owners to dietary and exercise recommendations, and evaluate the efficacy of dietary and exercise recommendations. Animals - 40 Quarter Horses with PSSM and 37 unaffected control horses. Procedures - Owners of horses with PSSM completed a retrospective questionnaire concerning their horse's condition. Results - Between horses with PSSM and control horses, no significant differences were found in sex distribution (21 vs 15 females and 16 vs 22 males, respectively), temperament, muscle build, diet, or amount of turnout. In horses with PSSM, signs of muscle stiffness, muscle fasciculations, sweating, exercise intolerance, weakness, muscle wasting, reluctance to move, colic, abnormal gait, recumbency, lameness, and swollen muscles began between the age of 1 day and 14 years (mean age, 4.9 ± 3.5 years). Five horses with PSSM developed acute muscle atrophy. Sixty-three percent (25/40) of owners fed the recommended diet, 55% (22/40) provided regular exercise, and 40% (16/40) followed both dietary and exercise recommendations. Owners of affected horses for which a decrease in severity or frequency of PSSM was not found did not follow the exercise, dietary, or both recommendations. All horses for which both dietary and exercise recommendations were followed had improvement in signs of PSSM. Conclusions and Clinical Relevance - In addition to exertional rhabdomyolysis, signs of PSSM include acute muscle atrophy and gait abnormalities. It appears that PSSM can be managed by following dietary recommendations combined with gradual increases in daily exercise.

UR - http://www.scopus.com/inward/record.url?scp=0141955861&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0141955861&partnerID=8YFLogxK

U2 - 10.2460/ajvr.2003.64.1319

DO - 10.2460/ajvr.2003.64.1319

M3 - Article

VL - 64

SP - 1319

EP - 1327

JO - American Journal of Veterinary Research

JF - American Journal of Veterinary Research

SN - 0002-9645

IS - 10

ER -