Epidemic of acquired immunodeficiency in rhesus monkeys

R. V. Henrickson; D. H. Maul; K. G. Osborn; J. L. Sever; D. L. Madden; L. R. Ellingsworth; J. H. Anderson; Linda J Lowenstine; M. B. Gardner

doi:10.1016/S0140-6736(83)91503-9

Epidemic of acquired immunodeficiency in rhesus monkeys

R. V. Henrickson, D. H. Maul, K. G. Osborn, J. L. Sever, D. L. Madden, L. R. Ellingsworth, J. H. Anderson, Linda J Lowenstine, M. B. Gardner

Pathology, Microbiology and Immunology

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97 Scopus citations

Abstract

A syndrome closely resembling acquired immunodeficiency syndrome (AIDS) in man has been identified in a group of 64 rhesus monkeys (Macaca mulatta) maintained outdoors at the California Primate Research Center. The syndrome is characterised by generalised lymphadenopathy, severe opportunistic infections including cytomegalovirus, chronic wasting, and high mortality. In 1 animal a multifocal cutaneous fibrosarcoma developed. This syndrome in monkeys may provide an animal model for human AIDS.

Original language	English (US)
Pages (from-to)	388-390
Number of pages	3
Journal	Lancet
Volume	1
Issue number	8321
DOIs	https://doi.org/10.1016/S0140-6736(83)91503-9
State	Published - 1983

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ASJC Scopus subject areas

Medicine(all)

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Henrickson, R. V., Maul, D. H., Osborn, K. G., Sever, J. L., Madden, D. L., Ellingsworth, L. R., Anderson, J. H., Lowenstine, L. J., & Gardner, M. B. (1983). Epidemic of acquired immunodeficiency in rhesus monkeys. Lancet, 1(8321), 388-390. https://doi.org/10.1016/S0140-6736(83)91503-9

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abstract = "A syndrome closely resembling acquired immunodeficiency syndrome (AIDS) in man has been identified in a group of 64 rhesus monkeys (Macaca mulatta) maintained outdoors at the California Primate Research Center. The syndrome is characterised by generalised lymphadenopathy, severe opportunistic infections including cytomegalovirus, chronic wasting, and high mortality. In 1 animal a multifocal cutaneous fibrosarcoma developed. This syndrome in monkeys may provide an animal model for human AIDS.",

author = "Henrickson, {R. V.} and Maul, {D. H.} and Osborn, {K. G.} and Sever, {J. L.} and Madden, {D. L.} and Ellingsworth, {L. R.} and Anderson, {J. H.} and Lowenstine, {Linda J} and Gardner, {M. B.}",

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AU - Henrickson, R. V.

AU - Maul, D. H.

AU - Osborn, K. G.

AU - Sever, J. L.

AU - Madden, D. L.

AU - Ellingsworth, L. R.

AU - Anderson, J. H.

AU - Lowenstine, Linda J

AU - Gardner, M. B.

PY - 1983

Y1 - 1983

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10.1016/S0140-6736(83)91503-9