Epidemic of acquired immunodeficiency in rhesus monkeys

R. V. Henrickson; D. H. Maul; K. G. Osborn; J. L. Sever; D. L. Madden; L. R. Ellingsworth; J. H. Anderson; Linda J Lowenstine; M. B. Gardner

doi:10.1016/S0140-6736(83)91503-9

Epidemic of acquired immunodeficiency in rhesus monkeys

R. V. Henrickson, D. H. Maul, K. G. Osborn, J. L. Sever, D. L. Madden, L. R. Ellingsworth, J. H. Anderson, Linda J Lowenstine, M. B. Gardner

Pathology, Microbiology and Immunology

Research output: Contribution to journal › Article › peer-review

100 Scopus citations

Abstract

A syndrome closely resembling acquired immunodeficiency syndrome (AIDS) in man has been identified in a group of 64 rhesus monkeys (Macaca mulatta) maintained outdoors at the California Primate Research Center. The syndrome is characterised by generalised lymphadenopathy, severe opportunistic infections including cytomegalovirus, chronic wasting, and high mortality. In 1 animal a multifocal cutaneous fibrosarcoma developed. This syndrome in monkeys may provide an animal model for human AIDS.

Original language	English (US)
Pages (from-to)	388-390
Number of pages	3
Journal	Lancet
Volume	1
Issue number	8321
DOIs	https://doi.org/10.1016/S0140-6736(83)91503-9
State	Published - 1983

ASJC Scopus subject areas

Medicine(all)

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10.1016/S0140-6736(83)91503-9

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title = "Epidemic of acquired immunodeficiency in rhesus monkeys",

abstract = "A syndrome closely resembling acquired immunodeficiency syndrome (AIDS) in man has been identified in a group of 64 rhesus monkeys (Macaca mulatta) maintained outdoors at the California Primate Research Center. The syndrome is characterised by generalised lymphadenopathy, severe opportunistic infections including cytomegalovirus, chronic wasting, and high mortality. In 1 animal a multifocal cutaneous fibrosarcoma developed. This syndrome in monkeys may provide an animal model for human AIDS.",

author = "Henrickson, {R. V.} and Maul, {D. H.} and Osborn, {K. G.} and Sever, {J. L.} and Madden, {D. L.} and Ellingsworth, {L. R.} and Anderson, {J. H.} and Lowenstine, {Linda J} and Gardner, {M. B.}",

year = "1983",

doi = "10.1016/S0140-6736(83)91503-9",

language = "English (US)",

volume = "1",

pages = "388--390",

journal = "The Lancet",

issn = "0140-6736",

publisher = "Elsevier Limited",

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TY - JOUR

T1 - Epidemic of acquired immunodeficiency in rhesus monkeys

AU - Henrickson, R. V.

AU - Maul, D. H.

AU - Osborn, K. G.

AU - Sever, J. L.

AU - Madden, D. L.

AU - Ellingsworth, L. R.

AU - Anderson, J. H.

AU - Lowenstine, Linda J

AU - Gardner, M. B.

PY - 1983

Y1 - 1983

N2 - A syndrome closely resembling acquired immunodeficiency syndrome (AIDS) in man has been identified in a group of 64 rhesus monkeys (Macaca mulatta) maintained outdoors at the California Primate Research Center. The syndrome is characterised by generalised lymphadenopathy, severe opportunistic infections including cytomegalovirus, chronic wasting, and high mortality. In 1 animal a multifocal cutaneous fibrosarcoma developed. This syndrome in monkeys may provide an animal model for human AIDS.

AB - A syndrome closely resembling acquired immunodeficiency syndrome (AIDS) in man has been identified in a group of 64 rhesus monkeys (Macaca mulatta) maintained outdoors at the California Primate Research Center. The syndrome is characterised by generalised lymphadenopathy, severe opportunistic infections including cytomegalovirus, chronic wasting, and high mortality. In 1 animal a multifocal cutaneous fibrosarcoma developed. This syndrome in monkeys may provide an animal model for human AIDS.

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UR - http://www.scopus.com/inward/citedby.url?scp=0020661159&partnerID=8YFLogxK

U2 - 10.1016/S0140-6736(83)91503-9

DO - 10.1016/S0140-6736(83)91503-9

M3 - Article

C2 - 6130381

AN - SCOPUS:0020661159

VL - 1

SP - 388

EP - 390

JO - The Lancet

JF - The Lancet

SN - 0140-6736

IS - 8321

ER -

Epidemic of acquired immunodeficiency in rhesus monkeys

Abstract

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