Enzyme evolution: Generation of a bifunctional enzyme by fusion of adjacent genes

Joseph Yourno, Tadahiko Kohno, John R. Roth

Research output: Contribution to journalArticle

66 Scopus citations

Abstract

Two genes encoding distinct enzymes have been functionally fused by mutation. After fusion, the two genes act as one and produce a single polypeptide chain responsible for both catalytic activities.

Original languageEnglish (US)
Pages (from-to)820-824
Number of pages5
JournalNature
Volume228
Issue number5274
DOIs
StatePublished - 1970

ASJC Scopus subject areas

  • General

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