Abstract
Two genes encoding distinct enzymes have been functionally fused by mutation. After fusion, the two genes act as one and produce a single polypeptide chain responsible for both catalytic activities.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 820-824 |
| Number of pages | 5 |
| Journal | Nature |
| Volume | 228 |
| Issue number | 5274 |
| DOIs | |
| State | Published - 1970 |
ASJC Scopus subject areas
- General
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Yourno, J., Kohno, T., & Roth, J. R. (1970). Enzyme evolution: Generation of a bifunctional enzyme by fusion of adjacent genes. Nature, 228(5274), 820-824. https://doi.org/10.1038/228820a0