Abstract
Two genes encoding distinct enzymes have been functionally fused by mutation. After fusion, the two genes act as one and produce a single polypeptide chain responsible for both catalytic activities.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 820-824 |
| Number of pages | 5 |
| Journal | Nature |
| Volume | 228 |
| Issue number | 5274 |
| DOIs | |
| State | Published - 1970 |
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Cite this
Enzyme evolution : Generation of a bifunctional enzyme by fusion of adjacent genes. / Yourno, Joseph; Kohno, Tadahiko; Roth, John R.
In: Nature, Vol. 228, No. 5274, 1970, p. 820-824.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Enzyme evolution
T2 - Generation of a bifunctional enzyme by fusion of adjacent genes
AU - Yourno, Joseph
AU - Kohno, Tadahiko
AU - Roth, John R.
PY - 1970
Y1 - 1970
N2 - Two genes encoding distinct enzymes have been functionally fused by mutation. After fusion, the two genes act as one and produce a single polypeptide chain responsible for both catalytic activities.
AB - Two genes encoding distinct enzymes have been functionally fused by mutation. After fusion, the two genes act as one and produce a single polypeptide chain responsible for both catalytic activities.
UR - http://www.scopus.com/inward/record.url?scp=0014966626&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0014966626&partnerID=8YFLogxK
U2 - 10.1038/228820a0
DO - 10.1038/228820a0
M3 - Article
C2 - 4920435
AN - SCOPUS:0014966626
VL - 228
SP - 820
EP - 824
JO - Nature
JF - Nature
SN - 0028-0836
IS - 5274
ER -