Environmental factors associated with Bartonella vinsonii subsp. berkhoffii seropositivity in free-ranging coyotes from Northern California

P. M. Beldomenico, Bruno B Chomel, Janet E Foley, Benjamin Sacks, C. J. Baldi, R. W. Kasten, Ian Gardner

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Bartonella vinsonii subsp. berkhoffii is a newly recognized pathogen of domestic dogs and humans. Coyotes (Canis latrans) are considered an important reservoir of this bacterium in the western United States, but its vectors are still unknown. Our objective was to identify environmental factors associated with Bartonella antibody prevalence in 239 coyotes from northern California, using an enzyme-linked immunosorbent assay. In addition, associations were evaluated between B. v. berkhoffii and two pathogens with known vectors and habitat requirements, Dirofilaria immitis and Anaplasma phagocytophilum. Overall, B. v. berkhoffii seroprevalence was 28% (95% confidence interval [CI], 22.3%, 33.7%) and Bartonella seropositive coyotes were more likely than seronegative coyotes to be positive for Anaplasma phagocytophilum (Odds ratio=3.3; 95% CI=1.8, 5.9) and Dirofilaria immitis (Odds ratio=2.1; 95% CI=1.2, 3.8). The most likely geographic clusters of Bartonella and Dirofilaria overlapped. Bartonella seropositivity was associated with higher precipitation (p=0.003) and proximity to the coast (p=0.007) in univariate analysis. The association with precipitation varied with season, based on a logistic regression model.

Original languageEnglish (US)
Pages (from-to)110-119
Number of pages10
JournalVector-Borne and Zoonotic Diseases
Volume5
Issue number2
DOIs
StatePublished - Jun 2005

Fingerprint

Coyotes
Bartonella
Anaplasma phagocytophilum
Dirofilaria immitis
Confidence Intervals
Dirofilaria
Logistic Models
Odds Ratio
Seroepidemiologic Studies
Ecosystem
Enzyme-Linked Immunosorbent Assay
Dogs
Bacteria
Antibodies

Keywords

  • Bartonella vinsonii subsp. berkhoffii
  • Canis latrans
  • Coyote
  • Epidemiology

ASJC Scopus subject areas

  • Infectious Diseases
  • Parasitology

Cite this

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title = "Environmental factors associated with Bartonella vinsonii subsp. berkhoffii seropositivity in free-ranging coyotes from Northern California",
abstract = "Bartonella vinsonii subsp. berkhoffii is a newly recognized pathogen of domestic dogs and humans. Coyotes (Canis latrans) are considered an important reservoir of this bacterium in the western United States, but its vectors are still unknown. Our objective was to identify environmental factors associated with Bartonella antibody prevalence in 239 coyotes from northern California, using an enzyme-linked immunosorbent assay. In addition, associations were evaluated between B. v. berkhoffii and two pathogens with known vectors and habitat requirements, Dirofilaria immitis and Anaplasma phagocytophilum. Overall, B. v. berkhoffii seroprevalence was 28{\%} (95{\%} confidence interval [CI], 22.3{\%}, 33.7{\%}) and Bartonella seropositive coyotes were more likely than seronegative coyotes to be positive for Anaplasma phagocytophilum (Odds ratio=3.3; 95{\%} CI=1.8, 5.9) and Dirofilaria immitis (Odds ratio=2.1; 95{\%} CI=1.2, 3.8). The most likely geographic clusters of Bartonella and Dirofilaria overlapped. Bartonella seropositivity was associated with higher precipitation (p=0.003) and proximity to the coast (p=0.007) in univariate analysis. The association with precipitation varied with season, based on a logistic regression model.",
keywords = "Bartonella vinsonii subsp. berkhoffii, Canis latrans, Coyote, Epidemiology",
author = "Beldomenico, {P. M.} and Chomel, {Bruno B} and Foley, {Janet E} and Benjamin Sacks and Baldi, {C. J.} and Kasten, {R. W.} and Ian Gardner",
year = "2005",
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T1 - Environmental factors associated with Bartonella vinsonii subsp. berkhoffii seropositivity in free-ranging coyotes from Northern California

AU - Beldomenico, P. M.

AU - Chomel, Bruno B

AU - Foley, Janet E

AU - Sacks, Benjamin

AU - Baldi, C. J.

AU - Kasten, R. W.

AU - Gardner, Ian

PY - 2005/6

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