Enterotoxic clostridia: Clostridium perfringens enteric diseases

Archana Shrestha, Francisco A. Uzal, Bruce A. McClane

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations


Clostridium perfringens is a Gram-positive, spore-forming rod with ubiquitous environmental distribution, including a presence in soil and sewage (1-3). Given its anaerobic nature, it is unsurprising that C. perfringens is also a component of the normal gastrointestinal (GI) tract microbiota of humans and other animals (1, 2,4). Additionally, this bacterium is an important cause of intestinal and histotoxic infections in humans and other animals (2, 5, 6).

Original languageEnglish (US)
Title of host publicationGram-Positive Pathogens
Number of pages14
ISBN (Electronic)9781683670452
ISBN (Print)9781683670124
StatePublished - Jan 1 2019


  • Bystander killing effect
  • Clostridium perfringens
  • Cpe protein
  • Enteritis necroticans
  • Nonfood borne human gastrointestinal disease
  • Type F food poisoning

ASJC Scopus subject areas

  • Immunology and Microbiology(all)


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