Enteric coronavirus infection in adult horses

Nicola Pusterla, R. Vin, C. M. Leutenegger, L. D. Mittel, T. J. Divers

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

A new enteric virus of adult horses, equine coronavirus (ECoV), has recently been recognized. It is associated with fever, lethargy, anorexia, and less frequently, colic and diarrhea. This enteric virus is transmitted via the feco-oral route and horses become infected by ingesting fecally contaminated feed and water. Various outbreaks have been reported since 2010 from Japan, Europe and the USA. While the clinical signs are fairly non-specific, lymphopenia and neutropenia are often seen. Specific diagnosis is made by the detection of ECoV in feces by either quantitative real-time PCR, electron microscopy or antigen-capture ELISA. Supportive treatment is usually required, as most infections are self-limiting. However, rare complications, such as endotoxemia, septicemia and hyperammonemia-associated encephalopathy, have been reported, and have been related to the loss of barrier function at the intestinal mucosa. This review article will focus on the latest information pertaining to the virus, epidemiology, clinical signs, diagnosis, pathology, treatment and prevention of ECoV infection in adult horses.

Original languageEnglish (US)
Pages (from-to)13-18
Number of pages6
JournalVeterinary Journal
Volume231
DOIs
StatePublished - Jan 1 2018

Fingerprint

Coronavirus Infections
Coronavirinae
Horses
horses
infection
Enterovirus
Coronavirus
Hyperammonemia
neutropenia
endotoxemia
Lethargy
Lymphopenia
encephalopathy
feed contamination
Endotoxemia
Colic
colic
septicemia
Anorexia
Brain Diseases

Keywords

  • Clinical disease
  • Diagnosis
  • Epidemiology
  • Equine coronavirus
  • Treatment

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

Cite this

Pusterla, N., Vin, R., Leutenegger, C. M., Mittel, L. D., & Divers, T. J. (2018). Enteric coronavirus infection in adult horses. Veterinary Journal, 231, 13-18. https://doi.org/10.1016/j.tvjl.2017.11.004

Enteric coronavirus infection in adult horses. / Pusterla, Nicola; Vin, R.; Leutenegger, C. M.; Mittel, L. D.; Divers, T. J.

In: Veterinary Journal, Vol. 231, 01.01.2018, p. 13-18.

Research output: Contribution to journalArticle

Pusterla, N, Vin, R, Leutenegger, CM, Mittel, LD & Divers, TJ 2018, 'Enteric coronavirus infection in adult horses', Veterinary Journal, vol. 231, pp. 13-18. https://doi.org/10.1016/j.tvjl.2017.11.004
Pusterla, Nicola ; Vin, R. ; Leutenegger, C. M. ; Mittel, L. D. ; Divers, T. J. / Enteric coronavirus infection in adult horses. In: Veterinary Journal. 2018 ; Vol. 231. pp. 13-18.
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