Engineered muscle: A tool for studying muscle physiology and function

Alastair Khodabukus; Jennifer Z. Paxton; Kenneth Donnelly; Keith Baar

doi:10.1097/jes.0b013e318156df01

Engineered muscle: A tool for studying muscle physiology and function

Alastair Khodabukus, Jennifer Z. Paxton, Kenneth Donnelly, Keith Baar

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

Recent advances in skeletal muscle tissue engineering have resulted in an in vitro tissue model that can be used for studying the effects of genetic alterations, pharmacological interventions, and exercise on muscle physiology and function. Here, we present applications for this technology to further our understanding of the molecular mechanisms underlying skeletal muscle adaptation in response to exercise.

Original language	English (US)
Pages (from-to)	186-191
Number of pages	6
Journal	Exercise and Sport Sciences Reviews
Volume	35
Issue number	4
DOIs	https://doi.org/10.1097/jes.0b013e318156df01
State	Published - Oct 2007
Externally published	Yes

Keywords

Exercise
Fiber type
Muscle development
Muscle function
Tissue engineering

ASJC Scopus subject areas

Public Health, Environmental and Occupational Health
Endocrinology
Orthopedics and Sports Medicine
Physical Therapy, Sports Therapy and Rehabilitation

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10.1097/jes.0b013e318156df01

Cite this

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abstract = "Recent advances in skeletal muscle tissue engineering have resulted in an in vitro tissue model that can be used for studying the effects of genetic alterations, pharmacological interventions, and exercise on muscle physiology and function. Here, we present applications for this technology to further our understanding of the molecular mechanisms underlying skeletal muscle adaptation in response to exercise.",

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author = "Alastair Khodabukus and Paxton, {Jennifer Z.} and Kenneth Donnelly and Keith Baar",

year = "2007",

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AU - Paxton, Jennifer Z.

AU - Donnelly, Kenneth

AU - Baar, Keith

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AB - Recent advances in skeletal muscle tissue engineering have resulted in an in vitro tissue model that can be used for studying the effects of genetic alterations, pharmacological interventions, and exercise on muscle physiology and function. Here, we present applications for this technology to further our understanding of the molecular mechanisms underlying skeletal muscle adaptation in response to exercise.

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KW - Fiber type

KW - Muscle development

KW - Muscle function

KW - Tissue engineering

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Engineered muscle: A tool for studying muscle physiology and function

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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