Engineered muscle: A tool for studying muscle physiology and function

Alastair Khodabukus, Jennifer Z. Paxton, Kenneth Donnelly, Keith Baar

Research output: Contribution to journalArticle

22 Scopus citations

Abstract

Recent advances in skeletal muscle tissue engineering have resulted in an in vitro tissue model that can be used for studying the effects of genetic alterations, pharmacological interventions, and exercise on muscle physiology and function. Here, we present applications for this technology to further our understanding of the molecular mechanisms underlying skeletal muscle adaptation in response to exercise.

Original languageEnglish (US)
Pages (from-to)186-191
Number of pages6
JournalExercise and Sport Sciences Reviews
Volume35
Issue number4
DOIs
StatePublished - Oct 2007
Externally publishedYes

Keywords

  • Exercise
  • Fiber type
  • Muscle development
  • Muscle function
  • Tissue engineering

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Endocrinology
  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation

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