Energy expenditure of adult male rhesus monkeys during the first 30 mo of dietary restriction

Jon J Ramsey, Ellen B. Roecker, Richard Weindruch, Joseph W. Kemnitz

Research output: Contribution to journalArticlepeer-review

46 Scopus citations


Energy expenditure, activity, and body composition were measured in 30 adult male rhesus monkeys used in a study having the long-term goal of determining the effects of moderate dietary restriction (DR) on aging. All animals were fed a defined diet, with the restricted animals maintained at ~70% of the caloric intakes of the controls. After 12 mo of DR, body fat mass of restricted monkeys was 33% less than that of controls (P = 0.004), whereas lean body mass differences were not present until after 24 mo. At the 24- and 30-mo assessments, nighttime energy expenditure was significantly reduced (P < 0.01) in the restricted compared with control monkeys after adjustment for lean body mass differences, whereas morning, afternoon, and total energy expenditure were not significantly different (P > 0.05). No significant differences (P > 0.05) in activity were noticed between treatment groups at any time point. DR resulted in a prolonged decrease in resting energy expenditure, which could contribute to the possible life-extending action of this treatment.

Original languageEnglish (US)
JournalAmerican Journal of Physiology - Endocrinology and Metabolism
Issue number5 35-5
StatePublished - May 1997
Externally publishedYes


  • activity
  • aging
  • body composition
  • oxygen consumption

ASJC Scopus subject areas

  • Physiology
  • Endocrinology
  • Biochemistry
  • Physiology (medical)


Dive into the research topics of 'Energy expenditure of adult male rhesus monkeys during the first 30 mo of dietary restriction'. Together they form a unique fingerprint.

Cite this