Endotoxin-induced structural transformations in liquid crystalline droplets

I. Hsin Lin, Daniel S. Miller, Paul J. Bertics, Christopher J Murphy, Juan J. De Pablo, Nicholas L. Abbott

Research output: Contribution to journalArticle

208 Citations (Scopus)

Abstract

The ordering of liquid crystals (LCs) is known to be influenced by surfaces and contaminants. Here, we report that picogram per milliliter concentrations of endotoxin in water trigger ordering transitions in micrometer-size LC droplets. The ordering transitions, which occur at surface concentrations of endotoxin that are less than 10 -5 Langmuir, are not due to adsorbate-induced changes in the interfacial energy of the LC. The sensitivity of the LC to endotoxin was measured to change by six orders of magnitude with the geometry of the LC (droplet versus slab), supporting the hypothesis that interactions of endotoxin with topological defects in the LC mediate the response of the droplets. The LC ordering transitions depend strongly on glycophospholipid structure and provide new designs for responsive soft matter.

Original languageEnglish (US)
Pages (from-to)1297-1300
Number of pages4
JournalScience
Volume332
Issue number6035
DOIs
StatePublished - Jun 10 2011

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Liquid Crystals
Endotoxins
Water

ASJC Scopus subject areas

  • General

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Lin, I. H., Miller, D. S., Bertics, P. J., Murphy, C. J., De Pablo, J. J., & Abbott, N. L. (2011). Endotoxin-induced structural transformations in liquid crystalline droplets. Science, 332(6035), 1297-1300. https://doi.org/10.1126/science.1195639

Endotoxin-induced structural transformations in liquid crystalline droplets. / Lin, I. Hsin; Miller, Daniel S.; Bertics, Paul J.; Murphy, Christopher J; De Pablo, Juan J.; Abbott, Nicholas L.

In: Science, Vol. 332, No. 6035, 10.06.2011, p. 1297-1300.

Research output: Contribution to journalArticle

Lin, IH, Miller, DS, Bertics, PJ, Murphy, CJ, De Pablo, JJ & Abbott, NL 2011, 'Endotoxin-induced structural transformations in liquid crystalline droplets', Science, vol. 332, no. 6035, pp. 1297-1300. https://doi.org/10.1126/science.1195639
Lin IH, Miller DS, Bertics PJ, Murphy CJ, De Pablo JJ, Abbott NL. Endotoxin-induced structural transformations in liquid crystalline droplets. Science. 2011 Jun 10;332(6035):1297-1300. https://doi.org/10.1126/science.1195639
Lin, I. Hsin ; Miller, Daniel S. ; Bertics, Paul J. ; Murphy, Christopher J ; De Pablo, Juan J. ; Abbott, Nicholas L. / Endotoxin-induced structural transformations in liquid crystalline droplets. In: Science. 2011 ; Vol. 332, No. 6035. pp. 1297-1300.
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