Abstract
OBJECTIVE: We investigated the association between endometritis and reproductive morbidity. STUDY DESIGN: Participants were 614 women in the PID Evaluation and Clinical Health (PEACH) Study with pelvic pain, pelvic organ tenderness, and leukorrhea, mucopurulent cervicitis, or untreated cervicitis. We compared women with endometritis (≥5 neutrophils or ≥2 plasma cells), Neisseria gonorrhoeae or Chlamydia trachomatis upper genital tract infection (UGTI) or both to women without endometritis/UGTI for outcomes of pregnancy, infertility, recurrent pelvic inflammatory disease (PID), and chronic pelvic pain (CPP), adjusting for age, race, education, PID history, and baseline infertility. RESULTS: Endometritis/UGTI was not associated with reduced pregnancy (odds ratio [OR] 0.8, 95% CI 0.6-1.2) or elevated infertility (OR 1.0, 95% CI 0.6-1.6), recurrent PID (OR 0.6, 95% CI 0.4-0.9), or CPP (OR 0.6, 95% CI 0.4-0.9). PEACH participants with and without endometritis/UGTI had higher age- and race-specific pregnancy rates than 1997 national rates. CONCLUSION: Among women with clinically suspected mild-to-moderate PID treated with standard antibiotics, endometritis/UGTI was not associated with reproductive morbidity.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 141-148 |
| Number of pages | 8 |
| Journal | American Journal of Obstetrics and Gynecology |
| Volume | 188 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 1 2003 |
| Externally published | Yes |
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Keywords
- Chronic pelvic pain
- Endometritis
- Infertility
- Pregnancy
- Salpingitis
ASJC Scopus subject areas
- Medicine(all)
- Obstetrics and Gynecology
Cite this
Endometritis does not predict reproductive morbidity after pelvic inflammatory disease. / Haggerty, Catherine L.; Ness, Roberta B.; Amortegui, Antonio; Hendrix, Susan L.; Hillier, Sharon L.; Holley, Robert L.; Peipert, Jeffrey; Randall, Hugh; Sondheimer, Steven J.; Soper, David E.; Sweet, Richard L; Trucco, Guiliana.
In: American Journal of Obstetrics and Gynecology, Vol. 188, No. 1, 01.01.2003, p. 141-148.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Endometritis does not predict reproductive morbidity after pelvic inflammatory disease
AU - Haggerty, Catherine L.
AU - Ness, Roberta B.
AU - Amortegui, Antonio
AU - Hendrix, Susan L.
AU - Hillier, Sharon L.
AU - Holley, Robert L.
AU - Peipert, Jeffrey
AU - Randall, Hugh
AU - Sondheimer, Steven J.
AU - Soper, David E.
AU - Sweet, Richard L
AU - Trucco, Guiliana
PY - 2003/1/1
Y1 - 2003/1/1
N2 - OBJECTIVE: We investigated the association between endometritis and reproductive morbidity. STUDY DESIGN: Participants were 614 women in the PID Evaluation and Clinical Health (PEACH) Study with pelvic pain, pelvic organ tenderness, and leukorrhea, mucopurulent cervicitis, or untreated cervicitis. We compared women with endometritis (≥5 neutrophils or ≥2 plasma cells), Neisseria gonorrhoeae or Chlamydia trachomatis upper genital tract infection (UGTI) or both to women without endometritis/UGTI for outcomes of pregnancy, infertility, recurrent pelvic inflammatory disease (PID), and chronic pelvic pain (CPP), adjusting for age, race, education, PID history, and baseline infertility. RESULTS: Endometritis/UGTI was not associated with reduced pregnancy (odds ratio [OR] 0.8, 95% CI 0.6-1.2) or elevated infertility (OR 1.0, 95% CI 0.6-1.6), recurrent PID (OR 0.6, 95% CI 0.4-0.9), or CPP (OR 0.6, 95% CI 0.4-0.9). PEACH participants with and without endometritis/UGTI had higher age- and race-specific pregnancy rates than 1997 national rates. CONCLUSION: Among women with clinically suspected mild-to-moderate PID treated with standard antibiotics, endometritis/UGTI was not associated with reproductive morbidity.
AB - OBJECTIVE: We investigated the association between endometritis and reproductive morbidity. STUDY DESIGN: Participants were 614 women in the PID Evaluation and Clinical Health (PEACH) Study with pelvic pain, pelvic organ tenderness, and leukorrhea, mucopurulent cervicitis, or untreated cervicitis. We compared women with endometritis (≥5 neutrophils or ≥2 plasma cells), Neisseria gonorrhoeae or Chlamydia trachomatis upper genital tract infection (UGTI) or both to women without endometritis/UGTI for outcomes of pregnancy, infertility, recurrent pelvic inflammatory disease (PID), and chronic pelvic pain (CPP), adjusting for age, race, education, PID history, and baseline infertility. RESULTS: Endometritis/UGTI was not associated with reduced pregnancy (odds ratio [OR] 0.8, 95% CI 0.6-1.2) or elevated infertility (OR 1.0, 95% CI 0.6-1.6), recurrent PID (OR 0.6, 95% CI 0.4-0.9), or CPP (OR 0.6, 95% CI 0.4-0.9). PEACH participants with and without endometritis/UGTI had higher age- and race-specific pregnancy rates than 1997 national rates. CONCLUSION: Among women with clinically suspected mild-to-moderate PID treated with standard antibiotics, endometritis/UGTI was not associated with reproductive morbidity.
KW - Chronic pelvic pain
KW - Endometritis
KW - Infertility
KW - Pregnancy
KW - Salpingitis
UR - http://www.scopus.com/inward/record.url?scp=0037246399&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0037246399&partnerID=8YFLogxK
U2 - 10.1067/mob.2003.87
DO - 10.1067/mob.2003.87
M3 - Article
VL - 188
SP - 141
EP - 148
JO - American Journal of Obstetrics and Gynecology
JF - American Journal of Obstetrics and Gynecology
SN - 0002-9378
IS - 1
ER -