Abstract
Objectives: To assess if there was any potential relationship between endometrial thickness and final treatment outcome in women successfully treated with misoprostol for a first trimester anembryonic gestation, embryonic demise or fetal demise. Methods: Eighty women were treated with up to two doses of misoprostol 800 μg vaginally for early pregnancy failure. Subjects were scheduled to return 2 (range 1-4), 7 (range 5-9) and 14 (range 12-17) days after treatment. Transvaginal ultrasonography was performed at each follow-up visit. Results: The median endometrial thickness at each of the follow-up visits for women who had expelled the gestational sac was 14 mm, 10 mm, and 7 mm, respectively. The endometrial thickness at the first follow-up visit exceeded 15 mm in 20 subjects (36%) and 30 mm in four subjects (7%). Only three women had a suction aspiration for bleeding after documented expulsion. The endometrial thickness for these women was 11, 13, and 14 mm at the first follow-up visit. Conclusions: There is no obvious relationship between increasing endometrial thickness and the need for surgical intervention in women treated with misoprostol for early pregnancy failure.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 22-26 |
| Number of pages | 5 |
| Journal | International Journal of Gynecology and Obstetrics |
| Volume | 86 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jul 2004 |
| Externally published | Yes |
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Keywords
- Early pregnancy failure
- endometrial thickness
- Miscarriage
- Misoprostol
- Transvaginal ultrasound
ASJC Scopus subject areas
- Obstetrics and Gynecology
Cite this
Endometrial thickness after misoprostol use for early pregnancy failure. / Creinin, Mitchell D; Harwood, B.; Guido, R. S.; Fox, M. C.; Zhang, J.
In: International Journal of Gynecology and Obstetrics, Vol. 86, No. 1, 07.2004, p. 22-26.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Endometrial thickness after misoprostol use for early pregnancy failure
AU - Creinin, Mitchell D
AU - Harwood, B.
AU - Guido, R. S.
AU - Fox, M. C.
AU - Zhang, J.
PY - 2004/7
Y1 - 2004/7
N2 - Objectives: To assess if there was any potential relationship between endometrial thickness and final treatment outcome in women successfully treated with misoprostol for a first trimester anembryonic gestation, embryonic demise or fetal demise. Methods: Eighty women were treated with up to two doses of misoprostol 800 μg vaginally for early pregnancy failure. Subjects were scheduled to return 2 (range 1-4), 7 (range 5-9) and 14 (range 12-17) days after treatment. Transvaginal ultrasonography was performed at each follow-up visit. Results: The median endometrial thickness at each of the follow-up visits for women who had expelled the gestational sac was 14 mm, 10 mm, and 7 mm, respectively. The endometrial thickness at the first follow-up visit exceeded 15 mm in 20 subjects (36%) and 30 mm in four subjects (7%). Only three women had a suction aspiration for bleeding after documented expulsion. The endometrial thickness for these women was 11, 13, and 14 mm at the first follow-up visit. Conclusions: There is no obvious relationship between increasing endometrial thickness and the need for surgical intervention in women treated with misoprostol for early pregnancy failure.
AB - Objectives: To assess if there was any potential relationship between endometrial thickness and final treatment outcome in women successfully treated with misoprostol for a first trimester anembryonic gestation, embryonic demise or fetal demise. Methods: Eighty women were treated with up to two doses of misoprostol 800 μg vaginally for early pregnancy failure. Subjects were scheduled to return 2 (range 1-4), 7 (range 5-9) and 14 (range 12-17) days after treatment. Transvaginal ultrasonography was performed at each follow-up visit. Results: The median endometrial thickness at each of the follow-up visits for women who had expelled the gestational sac was 14 mm, 10 mm, and 7 mm, respectively. The endometrial thickness at the first follow-up visit exceeded 15 mm in 20 subjects (36%) and 30 mm in four subjects (7%). Only three women had a suction aspiration for bleeding after documented expulsion. The endometrial thickness for these women was 11, 13, and 14 mm at the first follow-up visit. Conclusions: There is no obvious relationship between increasing endometrial thickness and the need for surgical intervention in women treated with misoprostol for early pregnancy failure.
KW - Early pregnancy failure
KW - endometrial thickness
KW - Miscarriage
KW - Misoprostol
KW - Transvaginal ultrasound
UR - http://www.scopus.com/inward/record.url?scp=2942669886&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=2942669886&partnerID=8YFLogxK
U2 - 10.1016/j.ijgo.2004.02.004
DO - 10.1016/j.ijgo.2004.02.004
M3 - Article
C2 - 15207665
AN - SCOPUS:2942669886
VL - 86
SP - 22
EP - 26
JO - International Journal of Gynecology and Obstetrics
JF - International Journal of Gynecology and Obstetrics
SN - 0020-7292
IS - 1
ER -