Abstract
Objectives: To assess if there was any potential relationship between endometrial thickness and final treatment outcome in women successfully treated with misoprostol for a first trimester anembryonic gestation, embryonic demise or fetal demise. Methods: Eighty women were treated with up to two doses of misoprostol 800 μg vaginally for early pregnancy failure. Subjects were scheduled to return 2 (range 1-4), 7 (range 5-9) and 14 (range 12-17) days after treatment. Transvaginal ultrasonography was performed at each follow-up visit. Results: The median endometrial thickness at each of the follow-up visits for women who had expelled the gestational sac was 14 mm, 10 mm, and 7 mm, respectively. The endometrial thickness at the first follow-up visit exceeded 15 mm in 20 subjects (36%) and 30 mm in four subjects (7%). Only three women had a suction aspiration for bleeding after documented expulsion. The endometrial thickness for these women was 11, 13, and 14 mm at the first follow-up visit. Conclusions: There is no obvious relationship between increasing endometrial thickness and the need for surgical intervention in women treated with misoprostol for early pregnancy failure.
Original language | English (US) |
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Pages (from-to) | 22-26 |
Number of pages | 5 |
Journal | International Journal of Gynecology and Obstetrics |
Volume | 86 |
Issue number | 1 |
DOIs | |
State | Published - Jul 2004 |
Externally published | Yes |
Keywords
- Early pregnancy failure
- endometrial thickness
- Miscarriage
- Misoprostol
- Transvaginal ultrasound
ASJC Scopus subject areas
- Obstetrics and Gynecology