Endocrinopathies in children infected with human immunodeficiency virus

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4 Citations (Scopus)

Abstract

Endocrine changes (including adrenal insufficiency, disorders of growth and puberty, thyroid dysfunction, metabolic abnormalities and osteopenia) accompany human immunodeficiency virus (HIV) infection in pediatric patients. The cause of these changes is multifactorial and includes direct viral effects of HIV, and effects of antiretroviral therapy. These effects may be of particular importance in childhood given the critical developmental processes that occur during this time period and the likelihood of prolonged exposure to the virus and medications.

Original languageEnglish (US)
Pages (from-to)807-828
Number of pages22
JournalEndocrinology and Metabolism Clinics of North America
Volume43
Issue number3
DOIs
StatePublished - 2014

Fingerprint

HIV
Growth Disorders
Adrenal Insufficiency
Metabolic Bone Diseases
Virus Diseases
Puberty
Thyroid Gland
Pediatrics
Viruses
Therapeutics

Keywords

  • Adrenal
  • Children
  • Dyslipidemia
  • Endocrinopathy
  • HIV
  • Insulin resistance
  • Lipodystrophy
  • Thyroid

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism

Cite this

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title = "Endocrinopathies in children infected with human immunodeficiency virus",
abstract = "Endocrine changes (including adrenal insufficiency, disorders of growth and puberty, thyroid dysfunction, metabolic abnormalities and osteopenia) accompany human immunodeficiency virus (HIV) infection in pediatric patients. The cause of these changes is multifactorial and includes direct viral effects of HIV, and effects of antiretroviral therapy. These effects may be of particular importance in childhood given the critical developmental processes that occur during this time period and the likelihood of prolonged exposure to the virus and medications.",
keywords = "Adrenal, Children, Dyslipidemia, Endocrinopathy, HIV, Insulin resistance, Lipodystrophy, Thyroid",
author = "Loomba-Albrecht, {Lindsey A} and Thea Bregman and Chantry, {Caroline J}",
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T1 - Endocrinopathies in children infected with human immunodeficiency virus

AU - Loomba-Albrecht, Lindsey A

AU - Bregman, Thea

AU - Chantry, Caroline J

PY - 2014

Y1 - 2014

N2 - Endocrine changes (including adrenal insufficiency, disorders of growth and puberty, thyroid dysfunction, metabolic abnormalities and osteopenia) accompany human immunodeficiency virus (HIV) infection in pediatric patients. The cause of these changes is multifactorial and includes direct viral effects of HIV, and effects of antiretroviral therapy. These effects may be of particular importance in childhood given the critical developmental processes that occur during this time period and the likelihood of prolonged exposure to the virus and medications.

AB - Endocrine changes (including adrenal insufficiency, disorders of growth and puberty, thyroid dysfunction, metabolic abnormalities and osteopenia) accompany human immunodeficiency virus (HIV) infection in pediatric patients. The cause of these changes is multifactorial and includes direct viral effects of HIV, and effects of antiretroviral therapy. These effects may be of particular importance in childhood given the critical developmental processes that occur during this time period and the likelihood of prolonged exposure to the virus and medications.

KW - Adrenal

KW - Children

KW - Dyslipidemia

KW - Endocrinopathy

KW - HIV

KW - Insulin resistance

KW - Lipodystrophy

KW - Thyroid

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