Endocrinopathies in children infected with human immunodeficiency virus

Lindsey A Loomba-Albrecht; Thea Bregman; Caroline J Chantry

doi:10.1016/j.ecl.2014.06.001

Endocrinopathies in children infected with human immunodeficiency virus

Lindsey A Loomba-Albrecht, Thea Bregman, Caroline J Chantry

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Endocrine changes (including adrenal insufficiency, disorders of growth and puberty, thyroid dysfunction, metabolic abnormalities and osteopenia) accompany human immunodeficiency virus (HIV) infection in pediatric patients. The cause of these changes is multifactorial and includes direct viral effects of HIV, and effects of antiretroviral therapy. These effects may be of particular importance in childhood given the critical developmental processes that occur during this time period and the likelihood of prolonged exposure to the virus and medications.

Original language	English (US)
Pages (from-to)	807-828
Number of pages	22
Journal	Endocrinology and Metabolism Clinics of North America
Volume	43
Issue number	3
DOIs	https://doi.org/10.1016/j.ecl.2014.06.001
State	Published - 2014

Keywords

Adrenal
Children
Dyslipidemia
Endocrinopathy
HIV
Insulin resistance
Lipodystrophy
Thyroid

ASJC Scopus subject areas

Endocrinology
Endocrinology, Diabetes and Metabolism

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10.1016/j.ecl.2014.06.001

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AU - Loomba-Albrecht, Lindsey A

AU - Bregman, Thea

AU - Chantry, Caroline J

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N2 - Endocrine changes (including adrenal insufficiency, disorders of growth and puberty, thyroid dysfunction, metabolic abnormalities and osteopenia) accompany human immunodeficiency virus (HIV) infection in pediatric patients. The cause of these changes is multifactorial and includes direct viral effects of HIV, and effects of antiretroviral therapy. These effects may be of particular importance in childhood given the critical developmental processes that occur during this time period and the likelihood of prolonged exposure to the virus and medications.

AB - Endocrine changes (including adrenal insufficiency, disorders of growth and puberty, thyroid dysfunction, metabolic abnormalities and osteopenia) accompany human immunodeficiency virus (HIV) infection in pediatric patients. The cause of these changes is multifactorial and includes direct viral effects of HIV, and effects of antiretroviral therapy. These effects may be of particular importance in childhood given the critical developmental processes that occur during this time period and the likelihood of prolonged exposure to the virus and medications.

KW - Adrenal

KW - Children

KW - Dyslipidemia

KW - Endocrinopathy

KW - HIV

KW - Insulin resistance

KW - Lipodystrophy

KW - Thyroid

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ER -

Endocrinopathies in children infected with human immunodeficiency virus

Abstract

Keywords

ASJC Scopus subject areas

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