Abstract
Endocrine changes (including adrenal insufficiency, disorders of growth and puberty, thyroid dysfunction, metabolic abnormalities and osteopenia) accompany human immunodeficiency virus (HIV) infection in pediatric patients. The cause of these changes is multifactorial and includes direct viral effects of HIV, and effects of antiretroviral therapy. These effects may be of particular importance in childhood given the critical developmental processes that occur during this time period and the likelihood of prolonged exposure to the virus and medications.
Original language | English (US) |
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Pages (from-to) | 807-828 |
Number of pages | 22 |
Journal | Endocrinology and Metabolism Clinics of North America |
Volume | 43 |
Issue number | 3 |
DOIs | |
State | Published - 2014 |
Keywords
- Adrenal
- Children
- Dyslipidemia
- Endocrinopathy
- HIV
- Insulin resistance
- Lipodystrophy
- Thyroid
ASJC Scopus subject areas
- Endocrinology
- Endocrinology, Diabetes and Metabolism