End-stage renal disease as the presenting manifestation of renal systemic lupus erythematosus

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About one-half of all children with systemic lupus erythematosus have clinical evidence of renal disease at initial presentation, such as proteinuria and acute renal failure. Herein, we report a case of a teenager who presented with end-stage renal disease (ESRD) of uncertain etiology, and who was subsequently determined to have lupus. The purpose of this report is to make health-care professionals aware of this unusual presentation of renal lupus, which has never been reported before. Children presenting in ESRD should be worked-up for autoimmune diseases since the discovery of such a disease process may impact future decision-making, especially with respect to subsequent renal transplantation.

Original languageEnglish (US)
Pages (from-to)149-151
Number of pages3
JournalPediatric Nephrology
Issue number1
StatePublished - Jan 2007



  • Chronic kidney disease
  • ESRD
  • Glomerulonephritis
  • Lupus
  • SLE

ASJC Scopus subject areas

  • Nephrology
  • Pediatrics, Perinatology, and Child Health

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