Abstract
Ion trap mass spectrometry (ITMS) was employed to study chiral guest-exchange reactions in gas-phase complexes of amino acids and β-cyclodextrin. Enantioselectivity was obtained with a selected group of amino acids containing alkyl side chains. The selectivity for the amino acids increased with the size of the side chain except for Phe where the selectivity dropped off considerably. The results were consistent with those obtained earlier with Fourier-transform mass spectrometry (FTMS). The two mass analyzers were compared with regard to enantiomeric analysis.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 79-87 |
| Number of pages | 9 |
| Journal | International Journal of Mass Spectrometry |
| Volume | 219 |
| Issue number | 1 |
| DOIs | |
| State | Published - Aug 1 2002 |
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Keywords
- Cyclodextrin
- Enantioselectivity
- Ion trap
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Spectroscopy
Cite this
Enantioselective gas-phase ion-molecule reactions in a quadrupole ion trap. / Grigorean, Gabriela; Gronert, Scott; Lebrilla, Carlito B.
In: International Journal of Mass Spectrometry, Vol. 219, No. 1, 01.08.2002, p. 79-87.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Enantioselective gas-phase ion-molecule reactions in a quadrupole ion trap
AU - Grigorean, Gabriela
AU - Gronert, Scott
AU - Lebrilla, Carlito B
PY - 2002/8/1
Y1 - 2002/8/1
N2 - Ion trap mass spectrometry (ITMS) was employed to study chiral guest-exchange reactions in gas-phase complexes of amino acids and β-cyclodextrin. Enantioselectivity was obtained with a selected group of amino acids containing alkyl side chains. The selectivity for the amino acids increased with the size of the side chain except for Phe where the selectivity dropped off considerably. The results were consistent with those obtained earlier with Fourier-transform mass spectrometry (FTMS). The two mass analyzers were compared with regard to enantiomeric analysis.
AB - Ion trap mass spectrometry (ITMS) was employed to study chiral guest-exchange reactions in gas-phase complexes of amino acids and β-cyclodextrin. Enantioselectivity was obtained with a selected group of amino acids containing alkyl side chains. The selectivity for the amino acids increased with the size of the side chain except for Phe where the selectivity dropped off considerably. The results were consistent with those obtained earlier with Fourier-transform mass spectrometry (FTMS). The two mass analyzers were compared with regard to enantiomeric analysis.
KW - Cyclodextrin
KW - Enantioselectivity
KW - Ion trap
UR - http://www.scopus.com/inward/record.url?scp=0036684887&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036684887&partnerID=8YFLogxK
U2 - 10.1016/S1387-3806(02)00558-4
DO - 10.1016/S1387-3806(02)00558-4
M3 - Article
AN - SCOPUS:0036684887
VL - 219
SP - 79
EP - 87
JO - International Journal of Mass Spectrometry
JF - International Journal of Mass Spectrometry
SN - 1387-3806
IS - 1
ER -