Enantioselective gas-phase ion-molecule reactions in a quadrupole ion trap

Gabriela Grigorean, Scott Gronert, Carlito B Lebrilla

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

Ion trap mass spectrometry (ITMS) was employed to study chiral guest-exchange reactions in gas-phase complexes of amino acids and β-cyclodextrin. Enantioselectivity was obtained with a selected group of amino acids containing alkyl side chains. The selectivity for the amino acids increased with the size of the side chain except for Phe where the selectivity dropped off considerably. The results were consistent with those obtained earlier with Fourier-transform mass spectrometry (FTMS). The two mass analyzers were compared with regard to enantiomeric analysis.

Original languageEnglish (US)
Pages (from-to)79-87
Number of pages9
JournalInternational Journal of Mass Spectrometry
Volume219
Issue number1
DOIs
StatePublished - Aug 1 2002

Fingerprint

amino acids
Amino acids
quadrupoles
Gases
Ions
vapor phases
Amino Acids
Molecules
Mass spectrometry
mass spectroscopy
selectivity
molecules
ions
Enantioselectivity
Cyclodextrins
analyzers
Fourier transforms

Keywords

  • Cyclodextrin
  • Enantioselectivity
  • Ion trap

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Spectroscopy

Cite this

Enantioselective gas-phase ion-molecule reactions in a quadrupole ion trap. / Grigorean, Gabriela; Gronert, Scott; Lebrilla, Carlito B.

In: International Journal of Mass Spectrometry, Vol. 219, No. 1, 01.08.2002, p. 79-87.

Research output: Contribution to journalArticle

Grigorean, Gabriela ; Gronert, Scott ; Lebrilla, Carlito B. / Enantioselective gas-phase ion-molecule reactions in a quadrupole ion trap. In: International Journal of Mass Spectrometry. 2002 ; Vol. 219, No. 1. pp. 79-87.
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