En face projection imaging of the human choroidal layers with tracking SLO and swept source OCT angiography methods

Iwona Gorczynska; Justin Migacz; Robert Zawadzki; Narendran Sudheendran; Yifan Jian; Pavan K. Tiruveedhula; Austin Roorda; John S Werner

doi:10.1117/12.2183603

En face projection imaging of the human choroidal layers with tracking SLO and swept source OCT angiography methods

Iwona Gorczynska, Justin Migacz, Robert Zawadzki, Narendran Sudheendran, Yifan Jian, Pavan K. Tiruveedhula, Austin Roorda, John S Werner

Ophthalmology and Vision Science

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

3 Scopus citations

Abstract

We tested and compared the capability of multiple optical coherence tomography (OCT) angiography methods: phase variance, amplitude decorrelation and speckle variance, with application of the split spectrum technique, to image the choroiretinal complex of the human eye. To test the possibility of OCT imaging stability improvement we utilized a real-time tracking scanning laser ophthalmoscopy (TSLO) system combined with a swept source OCT setup. In addition, we implemented a post- processing volume averaging method for improved angiographic image quality and reduction of motion artifacts. The OCT system operated at the central wavelength of 1040nm to enable sufficient depth penetration into the choroid. Imaging was performed in the eyes of healthy volunteers and patients diagnosed with age-related macular degeneration.

Original language	English (US)
Title of host publication	European Conference on Biomedical Optics, ECBO 2015
Publisher	OSA - The Optical Society
ISBN (Print)	9781628417012
DOIs	https://doi.org/10.1117/12.2183603
State	Published - Jul 21 2014
Event	European Conference on Biomedical Optics, ECBO 2015 - Munich, Germany Duration: Jun 21 2015 → Jun 25 2015

Other

Other	European Conference on Biomedical Optics, ECBO 2015
Country	Germany
City	Munich
Period	6/21/15 → 6/25/15

Keywords

Amplitude decorrelation OCT
Angiography
Choriocapillaris
Choroid
Eye tracking
Fourier domain OCT
Optical coherence
Phase variance OCT
Scanning laser ophthalmoscopy
Speckle variance OCT
Swept source OCT

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Mechanics of Materials

Access to Document

10.1117/12.2183603

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En face projection imaging of the human choroidal layers with tracking SLO and swept source OCT angiography methods. / Gorczynska, Iwona; Migacz, Justin; Zawadzki, Robert; Sudheendran, Narendran; Jian, Yifan; Tiruveedhula, Pavan K.; Roorda, Austin; Werner, John S.

European Conference on Biomedical Optics, ECBO 2015. OSA - The Optical Society, 2014.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Gorczynska, I, Migacz, J, Zawadzki, R, Sudheendran, N, Jian, Y, Tiruveedhula, PK, Roorda, A & Werner, JS 2014, En face projection imaging of the human choroidal layers with tracking SLO and swept source OCT angiography methods. in European Conference on Biomedical Optics, ECBO 2015. OSA - The Optical Society, European Conference on Biomedical Optics, ECBO 2015, Munich, Germany, 6/21/15. https://doi.org/10.1117/12.2183603

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abstract = "We tested and compared the capability of multiple optical coherence tomography (OCT) angiography methods: phase variance, amplitude decorrelation and speckle variance, with application of the split spectrum technique, to image the choroiretinal complex of the human eye. To test the possibility of OCT imaging stability improvement we utilized a real-time tracking scanning laser ophthalmoscopy (TSLO) system combined with a swept source OCT setup. In addition, we implemented a post- processing volume averaging method for improved angiographic image quality and reduction of motion artifacts. The OCT system operated at the central wavelength of 1040nm to enable sufficient depth penetration into the choroid. Imaging was performed in the eyes of healthy volunteers and patients diagnosed with age-related macular degeneration.",

keywords = "Amplitude decorrelation OCT, Angiography, Choriocapillaris, Choroid, Eye tracking, Fourier domain OCT, Optical coherence, Phase variance OCT, Scanning laser ophthalmoscopy, Speckle variance OCT, Swept source OCT",

author = "Iwona Gorczynska and Justin Migacz and Robert Zawadzki and Narendran Sudheendran and Yifan Jian and Tiruveedhula, {Pavan K.} and Austin Roorda and Werner, {John S}",

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AU - Gorczynska, Iwona

AU - Migacz, Justin

AU - Zawadzki, Robert

AU - Sudheendran, Narendran

AU - Jian, Yifan

AU - Tiruveedhula, Pavan K.

AU - Roorda, Austin

AU - Werner, John S

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N2 - We tested and compared the capability of multiple optical coherence tomography (OCT) angiography methods: phase variance, amplitude decorrelation and speckle variance, with application of the split spectrum technique, to image the choroiretinal complex of the human eye. To test the possibility of OCT imaging stability improvement we utilized a real-time tracking scanning laser ophthalmoscopy (TSLO) system combined with a swept source OCT setup. In addition, we implemented a post- processing volume averaging method for improved angiographic image quality and reduction of motion artifacts. The OCT system operated at the central wavelength of 1040nm to enable sufficient depth penetration into the choroid. Imaging was performed in the eyes of healthy volunteers and patients diagnosed with age-related macular degeneration.

AB - We tested and compared the capability of multiple optical coherence tomography (OCT) angiography methods: phase variance, amplitude decorrelation and speckle variance, with application of the split spectrum technique, to image the choroiretinal complex of the human eye. To test the possibility of OCT imaging stability improvement we utilized a real-time tracking scanning laser ophthalmoscopy (TSLO) system combined with a swept source OCT setup. In addition, we implemented a post- processing volume averaging method for improved angiographic image quality and reduction of motion artifacts. The OCT system operated at the central wavelength of 1040nm to enable sufficient depth penetration into the choroid. Imaging was performed in the eyes of healthy volunteers and patients diagnosed with age-related macular degeneration.

KW - Amplitude decorrelation OCT

KW - Angiography

KW - Choriocapillaris

KW - Choroid

KW - Eye tracking

KW - Fourier domain OCT

KW - Optical coherence

KW - Phase variance OCT

KW - Scanning laser ophthalmoscopy

KW - Speckle variance OCT

KW - Swept source OCT

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PB - OSA - The Optical Society

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