Emerging trends in antibiotic resistance

Implications for emergency medicine

Ali Pourmand, Maryann Mazer-Amirshahi, Gregory Jasani, Larissa S May

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Background: Many bacteria are demonstrating increasing levels of resistance to commonly used antibiotics. While this has implications for the healthcare system as a whole, many patients infected with these resistant organisms will initially present to the emergency department (ED).The purpose of this review is to provide a summary of current trends in infections caused by the most clinically relevant resistant organisms encountered in emergency medicine. Methods: Bacteria were selected based on the Centers for Disease Control and Prevention's National Action Plan for Combating Antibiotic Resistant Bacteria, and PubMed database. Results: The following bacteria were included: methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococci, Escherichia coli, carbapenem-resistant Enterobacteriaceae, Neisseria gonorrhoeae, and Pseudomonas aeruginosa. All have shown increasing rates of resistance to one or more of the antibiotics commonly used to treat them. Increasing rates of antibiotic resistance are associated with worse clinical outcomes and greater healthcare costs. Conclusions: Antibiotic resistance is increasing and poses significant a risk to both the patient and public health as a whole. Appropriate choice of initial antibiotic is important in improving clinical outcomes, which is often the role of the ED provider. On a broader level, the ED must also take part in institutional efforts such as Antibiotic Stewardship Programs, which have been shown to decrease costs and rates of infection with resistant organisms. Ultimately, a multifaceted approach will be required to curb the threat of antibiotic-resistant bacteria.

Original languageEnglish (US)
JournalAmerican Journal of Emergency Medicine
DOIs
StateAccepted/In press - Feb 8 2017

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Emergency Medicine
Microbial Drug Resistance
Anti-Bacterial Agents
Bacteria
Hospital Emergency Service
Carbapenems
Neisseria gonorrhoeae
Enterobacteriaceae
Centers for Disease Control and Prevention (U.S.)
Methicillin-Resistant Staphylococcus aureus
Infection
PubMed
Health Care Costs
Pseudomonas aeruginosa
Public Health
Databases
Escherichia coli
Delivery of Health Care
Costs and Cost Analysis

ASJC Scopus subject areas

  • Emergency Medicine

Cite this

Emerging trends in antibiotic resistance : Implications for emergency medicine. / Pourmand, Ali; Mazer-Amirshahi, Maryann; Jasani, Gregory; May, Larissa S.

In: American Journal of Emergency Medicine, 08.02.2017.

Research output: Contribution to journalArticle

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