Emerging diagnostic challenges and characteristics of simian betaretrovirus infections in captive macaque colonies

Jo Ann L. Yee, Richard Grant, Koen K. Van Rompay, La Rene Kuller, Amanda Carpenter, Robin Watanabe, Rebeca Huebner, Brian Agricola, Jeremy Smedley, Jeffrey A Roberts

Research output: Contribution to journalArticle

Abstract

To better understand Simian betaretrovirus (SRV) seropositivity in virus-negative macaques, we transfused blood from SRV-infected or suspect donors into immunosuppressed naive recipients. Our results do not support typical SRV1-5 infection as the cause, but provide evidence for several possibilities including serological artifact, new/different SRV, or an endogenous virus.

Original languageEnglish (US)
Pages (from-to)149-153
Number of pages5
JournalJournal of Medical Primatology
Volume46
Issue number4
DOIs
StatePublished - Aug 1 2017

Fingerprint

Betaretrovirus
Macaca
Viruses
viruses
Infection
infection
seroprevalence
Artifacts
blood

Keywords

  • endogenous virus
  • PCR
  • serology
  • transfusion

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

Cite this

Emerging diagnostic challenges and characteristics of simian betaretrovirus infections in captive macaque colonies. / Yee, Jo Ann L.; Grant, Richard; Van Rompay, Koen K.; Kuller, La Rene; Carpenter, Amanda; Watanabe, Robin; Huebner, Rebeca; Agricola, Brian; Smedley, Jeremy; Roberts, Jeffrey A.

In: Journal of Medical Primatology, Vol. 46, No. 4, 01.08.2017, p. 149-153.

Research output: Contribution to journalArticle

Yee, JAL, Grant, R, Van Rompay, KK, Kuller, LR, Carpenter, A, Watanabe, R, Huebner, R, Agricola, B, Smedley, J & Roberts, JA 2017, 'Emerging diagnostic challenges and characteristics of simian betaretrovirus infections in captive macaque colonies', Journal of Medical Primatology, vol. 46, no. 4, pp. 149-153. https://doi.org/10.1111/jmp.12295
Yee, Jo Ann L. ; Grant, Richard ; Van Rompay, Koen K. ; Kuller, La Rene ; Carpenter, Amanda ; Watanabe, Robin ; Huebner, Rebeca ; Agricola, Brian ; Smedley, Jeremy ; Roberts, Jeffrey A. / Emerging diagnostic challenges and characteristics of simian betaretrovirus infections in captive macaque colonies. In: Journal of Medical Primatology. 2017 ; Vol. 46, No. 4. pp. 149-153.
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