Ellipsometry-based opto-fluidic platform for characterizing 10,000 biomolecular reactions on solid supports in real time and for identifying inhibitors against protein-receptor interactions

X. D. Zhu

Ellipsometry-based opto-fluidic platform for characterizing 10,000 biomolecular reactions on solid supports in real time and for identifying inhibitors against protein-receptor interactions

X. D. Zhu

Physics, Applied Physics

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

We developed an optical detection platform based on nulling ellipsometry for simultaneously characterizing 10,000 biomolecular reactions on solid supports and for highly efficient identification of inhibitory molecules against specific protein-protein interactions from large compound libraries.

Original language	English (US)
Title of host publication	2015 Conference on Lasers and Electro-Optics, CLEO 2015
Publisher	Institute of Electrical and Electronics Engineers Inc.
Volume	2015-August
ISBN (Electronic)	9781557529688
State	Published - Aug 10 2015
Event	Conference on Lasers and Electro-Optics, CLEO 2015 - San Jose, United States Duration: May 10 2015 → May 15 2015

Other

Other	Conference on Lasers and Electro-Optics, CLEO 2015
Country	United States
City	San Jose
Period	5/10/15 → 5/15/15

Keywords

Biomedical optical imaging
Compounds
Glass
Inhibitors
Probes
Proteins
Real-time systems

ASJC Scopus subject areas

Electrical and Electronic Engineering
Atomic and Molecular Physics, and Optics
Electronic, Optical and Magnetic Materials

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Ellipsometry-based opto-fluidic platform for characterizing 10,000 biomolecular reactions on solid supports in real time and for identifying inhibitors against protein-receptor interactions. / Zhu, X. D.

2015 Conference on Lasers and Electro-Optics, CLEO 2015. Vol. 2015-August Institute of Electrical and Electronics Engineers Inc., 2015. 7183676.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Zhu, XD 2015, Ellipsometry-based opto-fluidic platform for characterizing 10,000 biomolecular reactions on solid supports in real time and for identifying inhibitors against protein-receptor interactions. in 2015 Conference on Lasers and Electro-Optics, CLEO 2015. vol. 2015-August, 7183676, Institute of Electrical and Electronics Engineers Inc., Conference on Lasers and Electro-Optics, CLEO 2015, San Jose, United States, 5/10/15.

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KW - Probes

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VL - 2015-August

BT - 2015 Conference on Lasers and Electro-Optics, CLEO 2015

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Ellipsometry-based opto-fluidic platform for characterizing 10,000 biomolecular reactions on solid supports in real time and for identifying inhibitors against protein-receptor interactions

Abstract

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Keywords

ASJC Scopus subject areas

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