Abstract
We developed an optical detection platform based on nulling ellipsometry for simultaneously characterizing 10,000 biomolecular reactions on solid supports and for highly efficient identification of inhibitory molecules against specific protein-protein interactions from large compound libraries.
| Original language | English (US) |
|---|---|
| Title of host publication | 2015 Conference on Lasers and Electro-Optics, CLEO 2015 |
| Publisher | Institute of Electrical and Electronics Engineers Inc. |
| Volume | 2015-August |
| ISBN (Electronic) | 9781557529688 |
| State | Published - Aug 10 2015 |
| Event | Conference on Lasers and Electro-Optics, CLEO 2015 - San Jose, United States Duration: May 10 2015 → May 15 2015 |
Other
| Other | Conference on Lasers and Electro-Optics, CLEO 2015 |
|---|---|
| Country | United States |
| City | San Jose |
| Period | 5/10/15 → 5/15/15 |
Keywords
- Biomedical optical imaging
- Compounds
- Glass
- Inhibitors
- Probes
- Proteins
- Real-time systems
ASJC Scopus subject areas
- Electrical and Electronic Engineering
- Atomic and Molecular Physics, and Optics
- Electronic, Optical and Magnetic Materials
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Cite this
Zhu, X. D. (2015). Ellipsometry-based opto-fluidic platform for characterizing 10,000 biomolecular reactions on solid supports in real time and for identifying inhibitors against protein-receptor interactions. In 2015 Conference on Lasers and Electro-Optics, CLEO 2015 (Vol. 2015-August). [7183676] Institute of Electrical and Electronics Engineers Inc..