Ellipsometry-based opto-fluidic platform for characterizing 10,000 biomolecular reactions on solid supports in real time and for identifying inhibitors against protein-receptor interactions

X. D. Zhu

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We developed an optical detection platform based on nulling ellipsometry for simultaneously characterizing 10,000 biomolecular reactions on solid supports and for highly efficient identification of inhibitory molecules against specific protein-protein interactions from large compound libraries.

Original languageEnglish (US)
Title of host publicationCLEO: Science and Innovations, CLEO-SI 2015
PublisherOptical Society of America (OSA)
Pages2267
Number of pages1
ISBN (Print)9781557529688
DOIs
StatePublished - May 4 2015
EventCLEO: Science and Innovations, CLEO-SI 2015 - San Jose, United States
Duration: May 10 2015May 15 2015

Other

OtherCLEO: Science and Innovations, CLEO-SI 2015
CountryUnited States
CitySan Jose
Period5/10/155/15/15

Fingerprint

fluidics
Ellipsometry
Fluidics
inhibitors
ellipsometry
platforms
proteins
Proteins
interactions
Molecules
molecules

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Electrical and Electronic Engineering
  • Atomic and Molecular Physics, and Optics

Cite this

Ellipsometry-based opto-fluidic platform for characterizing 10,000 biomolecular reactions on solid supports in real time and for identifying inhibitors against protein-receptor interactions. / Zhu, X. D.

CLEO: Science and Innovations, CLEO-SI 2015. Optical Society of America (OSA), 2015. p. 2267.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Zhu, XD 2015, Ellipsometry-based opto-fluidic platform for characterizing 10,000 biomolecular reactions on solid supports in real time and for identifying inhibitors against protein-receptor interactions. in CLEO: Science and Innovations, CLEO-SI 2015. Optical Society of America (OSA), pp. 2267, CLEO: Science and Innovations, CLEO-SI 2015, San Jose, United States, 5/10/15. https://doi.org/10.1364/CLEO_AT.2015.JW2A.86
@inproceedings{2a43a6bf35d14613b92f4a6d64ac17d6,
title = "Ellipsometry-based opto-fluidic platform for characterizing 10,000 biomolecular reactions on solid supports in real time and for identifying inhibitors against protein-receptor interactions",
abstract = "We developed an optical detection platform based on nulling ellipsometry for simultaneously characterizing 10,000 biomolecular reactions on solid supports and for highly efficient identification of inhibitory molecules against specific protein-protein interactions from large compound libraries.",
author = "Zhu, {X. D.}",
year = "2015",
month = "5",
day = "4",
doi = "10.1364/CLEO_AT.2015.JW2A.86",
language = "English (US)",
isbn = "9781557529688",
pages = "2267",
booktitle = "CLEO: Science and Innovations, CLEO-SI 2015",
publisher = "Optical Society of America (OSA)",

}

TY - GEN

T1 - Ellipsometry-based opto-fluidic platform for characterizing 10,000 biomolecular reactions on solid supports in real time and for identifying inhibitors against protein-receptor interactions

AU - Zhu, X. D.

PY - 2015/5/4

Y1 - 2015/5/4

N2 - We developed an optical detection platform based on nulling ellipsometry for simultaneously characterizing 10,000 biomolecular reactions on solid supports and for highly efficient identification of inhibitory molecules against specific protein-protein interactions from large compound libraries.

AB - We developed an optical detection platform based on nulling ellipsometry for simultaneously characterizing 10,000 biomolecular reactions on solid supports and for highly efficient identification of inhibitory molecules against specific protein-protein interactions from large compound libraries.

UR - http://www.scopus.com/inward/record.url?scp=84935507674&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84935507674&partnerID=8YFLogxK

U2 - 10.1364/CLEO_AT.2015.JW2A.86

DO - 10.1364/CLEO_AT.2015.JW2A.86

M3 - Conference contribution

SN - 9781557529688

SP - 2267

BT - CLEO: Science and Innovations, CLEO-SI 2015

PB - Optical Society of America (OSA)

ER -