Electrophysiologic studies on locked-in patients

heterogeneity of findings

Vernon L. Towle, Ricardo A Maselli, Lawrence P. Bernstein, Jean Paul Spire

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Somatosensory evoked potentials, brain-stem auditory evoked potentials and electroencephalograms were obtained from 9 patients with the diagnosis of 'locked-in' syndrome. No pattern of evoked potential abnormality was specific to this syndrome, with findings ranging from bilaterally normal to unilaterally or bilaterally absent. The evoked potential studies complemented radiographic findings in defining the extent of the lesion and revealed that a portion of the pontine tegmentum was usually involved. Pathology from 2 patients corroborated the findings of the evoked potential studies. The value of evoked potential studies of patients with locked-in syndrome is to provide early objective evidence of brain-stem involvement independent of the clinical examination, EEG and radiographic studies.

Original languageEnglish (US)
Pages (from-to)419-426
Number of pages8
JournalElectroencephalography and Clinical Neurophysiology
Volume73
Issue number5
DOIs
StatePublished - 1989
Externally publishedYes

Fingerprint

Evoked Potentials
Quadriplegia
Electroencephalography
Somatosensory Evoked Potentials
Brain Stem Auditory Evoked Potentials
Brain Stem
Pathology

Keywords

  • Brain-stem audit ory evoked potential
  • Brain-stem infarct
  • Evoked potential
  • Locked-in syndrome
  • Somatosensory evoked potential

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Electrophysiologic studies on locked-in patients : heterogeneity of findings. / Towle, Vernon L.; Maselli, Ricardo A; Bernstein, Lawrence P.; Spire, Jean Paul.

In: Electroencephalography and Clinical Neurophysiology, Vol. 73, No. 5, 1989, p. 419-426.

Research output: Contribution to journalArticle

Towle, Vernon L. ; Maselli, Ricardo A ; Bernstein, Lawrence P. ; Spire, Jean Paul. / Electrophysiologic studies on locked-in patients : heterogeneity of findings. In: Electroencephalography and Clinical Neurophysiology. 1989 ; Vol. 73, No. 5. pp. 419-426.
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