Electron-dense subepithelial glomerular deposits in Henoch-Schonlein purpura syndrome

C. K. Kim, M. Aikawa, Sudesh P Makker

Research output: Contribution to journalArticle

11 Scopus citations

Abstract

A case of Henoch-Schonlein purpura (HSP) with renal lesions is presented. The clinical, laboratory, and morphologic findings revealed features commonly described in HSP. A renal biopsy revealed diffuse, generalized, proliferative glomerulonephritis. The unusual findings in this case were numerous electron-dense subepithelial deposits ('humps') and a few small intramembranous deposits ('humps') and a few small intramembranous deposits in the glomerular capillaries without deposits in the mesangium, mimicking those of acute poststreptococcal glomerulonephritis. The electron-dense deposits were well correlated with deposits of IgG, IgA, C3, C4, C1q, and fibrin-fibrinogen demonstrated by immunofluorescent microscopy.

Original languageEnglish (US)
Pages (from-to)595-598
Number of pages4
JournalArchives of Pathology and Laboratory Medicine
Volume103
Issue number11
StatePublished - 1979
Externally publishedYes

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Medical Laboratory Technology

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