Electrocardiographic findings associated with very low calorie dieting

H. C. Seim, J. E. Mitchell, Claire Pomeroy, M. De Zwaan

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

OBJECTIVE: To determine the safety of very low calorie diets (VLCD) in regard to their effects on cardiac function. DESIGN: EKG changes were analyzed for 126 women on a VLCD of 3349 kJ/d (800 kcal/d), EKGs were done when the diet was begun, after 3 months of dieting, and at a 6 month follow up after being off the diet for 3 months. SETTING: Subjects were solicited through advertisements and charged $1,000 for participating after being screened for age, weight, and health status. MAIN OUTCOME MEASURES: EKG QTc intervals, PR interval, QRS interval, ST-T wave changes, and heart rate. RESULTS: Over one-fourth (27.0%) of subjects had normal EKGs at all three time points studied, Sinus bradycardia was the most common abnormality, observed in 60 subjects (47.6%) on at least one of the three EKGs. Fifty-eight (46%) patients had EKGs with ST-T wave abnormalities observed on at least one of the EKGs. Eight subjects (6.4%) had prolonged QTc (more than one standard deviation beyond the average for women) intervals on at least one EKG. None of these eight persons had significant untoward medical consequences. CONCLUSION: A VLCD diet of 3349 kJ/d (800 kcal/d) for up to 3 months is not associated with significant electrocardiographic abnormalities or clinical cardiac complications, provided the patients have low cardiovascular risk at baseline.

Original languageEnglish (US)
Pages (from-to)817-819
Number of pages3
JournalInternational Journal of Obesity
Volume19
Issue number11
StatePublished - 1995
Externally publishedYes

Fingerprint

very low calorie diet
dieting
Electrocardiography
diet
Caloric Restriction
cardiac output
sinuses
health status
heart rate
Diet
Bradycardia
Health Status
Heart Rate
Safety
Weights and Measures

Keywords

  • EKG
  • Qtc interval
  • Very low calorie diets

ASJC Scopus subject areas

  • Food Science
  • Endocrinology
  • Medicine (miscellaneous)
  • Endocrinology, Diabetes and Metabolism
  • Public Health, Environmental and Occupational Health

Cite this

Seim, H. C., Mitchell, J. E., Pomeroy, C., & De Zwaan, M. (1995). Electrocardiographic findings associated with very low calorie dieting. International Journal of Obesity, 19(11), 817-819.

Electrocardiographic findings associated with very low calorie dieting. / Seim, H. C.; Mitchell, J. E.; Pomeroy, Claire; De Zwaan, M.

In: International Journal of Obesity, Vol. 19, No. 11, 1995, p. 817-819.

Research output: Contribution to journalArticle

Seim, HC, Mitchell, JE, Pomeroy, C & De Zwaan, M 1995, 'Electrocardiographic findings associated with very low calorie dieting', International Journal of Obesity, vol. 19, no. 11, pp. 817-819.
Seim HC, Mitchell JE, Pomeroy C, De Zwaan M. Electrocardiographic findings associated with very low calorie dieting. International Journal of Obesity. 1995;19(11):817-819.
Seim, H. C. ; Mitchell, J. E. ; Pomeroy, Claire ; De Zwaan, M. / Electrocardiographic findings associated with very low calorie dieting. In: International Journal of Obesity. 1995 ; Vol. 19, No. 11. pp. 817-819.
@article{16c69696ca2a4ddfa8485c4362ae1a17,
title = "Electrocardiographic findings associated with very low calorie dieting",
abstract = "OBJECTIVE: To determine the safety of very low calorie diets (VLCD) in regard to their effects on cardiac function. DESIGN: EKG changes were analyzed for 126 women on a VLCD of 3349 kJ/d (800 kcal/d), EKGs were done when the diet was begun, after 3 months of dieting, and at a 6 month follow up after being off the diet for 3 months. SETTING: Subjects were solicited through advertisements and charged $1,000 for participating after being screened for age, weight, and health status. MAIN OUTCOME MEASURES: EKG QTc intervals, PR interval, QRS interval, ST-T wave changes, and heart rate. RESULTS: Over one-fourth (27.0{\%}) of subjects had normal EKGs at all three time points studied, Sinus bradycardia was the most common abnormality, observed in 60 subjects (47.6{\%}) on at least one of the three EKGs. Fifty-eight (46{\%}) patients had EKGs with ST-T wave abnormalities observed on at least one of the EKGs. Eight subjects (6.4{\%}) had prolonged QTc (more than one standard deviation beyond the average for women) intervals on at least one EKG. None of these eight persons had significant untoward medical consequences. CONCLUSION: A VLCD diet of 3349 kJ/d (800 kcal/d) for up to 3 months is not associated with significant electrocardiographic abnormalities or clinical cardiac complications, provided the patients have low cardiovascular risk at baseline.",
keywords = "EKG, Qtc interval, Very low calorie diets",
author = "Seim, {H. C.} and Mitchell, {J. E.} and Claire Pomeroy and {De Zwaan}, M.",
year = "1995",
language = "English (US)",
volume = "19",
pages = "817--819",
journal = "International Journal of Obesity",
issn = "0307-0565",
publisher = "Nature Publishing Group",
number = "11",

}

TY - JOUR

T1 - Electrocardiographic findings associated with very low calorie dieting

AU - Seim, H. C.

AU - Mitchell, J. E.

AU - Pomeroy, Claire

AU - De Zwaan, M.

PY - 1995

Y1 - 1995

N2 - OBJECTIVE: To determine the safety of very low calorie diets (VLCD) in regard to their effects on cardiac function. DESIGN: EKG changes were analyzed for 126 women on a VLCD of 3349 kJ/d (800 kcal/d), EKGs were done when the diet was begun, after 3 months of dieting, and at a 6 month follow up after being off the diet for 3 months. SETTING: Subjects were solicited through advertisements and charged $1,000 for participating after being screened for age, weight, and health status. MAIN OUTCOME MEASURES: EKG QTc intervals, PR interval, QRS interval, ST-T wave changes, and heart rate. RESULTS: Over one-fourth (27.0%) of subjects had normal EKGs at all three time points studied, Sinus bradycardia was the most common abnormality, observed in 60 subjects (47.6%) on at least one of the three EKGs. Fifty-eight (46%) patients had EKGs with ST-T wave abnormalities observed on at least one of the EKGs. Eight subjects (6.4%) had prolonged QTc (more than one standard deviation beyond the average for women) intervals on at least one EKG. None of these eight persons had significant untoward medical consequences. CONCLUSION: A VLCD diet of 3349 kJ/d (800 kcal/d) for up to 3 months is not associated with significant electrocardiographic abnormalities or clinical cardiac complications, provided the patients have low cardiovascular risk at baseline.

AB - OBJECTIVE: To determine the safety of very low calorie diets (VLCD) in regard to their effects on cardiac function. DESIGN: EKG changes were analyzed for 126 women on a VLCD of 3349 kJ/d (800 kcal/d), EKGs were done when the diet was begun, after 3 months of dieting, and at a 6 month follow up after being off the diet for 3 months. SETTING: Subjects were solicited through advertisements and charged $1,000 for participating after being screened for age, weight, and health status. MAIN OUTCOME MEASURES: EKG QTc intervals, PR interval, QRS interval, ST-T wave changes, and heart rate. RESULTS: Over one-fourth (27.0%) of subjects had normal EKGs at all three time points studied, Sinus bradycardia was the most common abnormality, observed in 60 subjects (47.6%) on at least one of the three EKGs. Fifty-eight (46%) patients had EKGs with ST-T wave abnormalities observed on at least one of the EKGs. Eight subjects (6.4%) had prolonged QTc (more than one standard deviation beyond the average for women) intervals on at least one EKG. None of these eight persons had significant untoward medical consequences. CONCLUSION: A VLCD diet of 3349 kJ/d (800 kcal/d) for up to 3 months is not associated with significant electrocardiographic abnormalities or clinical cardiac complications, provided the patients have low cardiovascular risk at baseline.

KW - EKG

KW - Qtc interval

KW - Very low calorie diets

UR - http://www.scopus.com/inward/record.url?scp=0028872862&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028872862&partnerID=8YFLogxK

M3 - Article

VL - 19

SP - 817

EP - 819

JO - International Journal of Obesity

JF - International Journal of Obesity

SN - 0307-0565

IS - 11

ER -