Efficient system modeling of a high-resolution zoom-in PET scanner

Jian Zhou, Jinyi Qi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

We have proposed a zoom-in PET system that integrates a higher-resolution detector capable of measuring depth of interaction (DOI) into an existing scanner to obtain highresolution images of a targeted region with high-sensitivity. The system acquires coincidence events between the high-resolution detector and low-resolution detectors, as well as those between the low-resolution detectors. Because of the irregular system geometry and the use of a DOI detector, the system matrix of the zoom-in PET system requires far greater storage space than that of a conventional PET scanner, which also results in long computational time for image reconstruction. To address this issue, here we propose a system matrix factorization for the zoom-in PET to reduce the storage and computational cost while maintaining the accuracy in image reconstruction. The proposed factored system matrix consists of two major components: a detector response (or sinogram blurring) matrix and a geometrical projection matrix. We present a novel method to design the geometrical component and an iterative algorithm to estimate the detector response matrix. A 2D simulation study showed that the proposed method can reduce the storage space and reconstruction time by a factor of 5 without noticeable sacrifice in image quality.

Original languageEnglish (US)
Title of host publicationIEEE Nuclear Science Symposium Conference Record
Pages3501-3505
Number of pages5
DOIs
StatePublished - 2010
Event2010 IEEE Nuclear Science Symposium, Medical Imaging Conference, NSS/MIC 2010 and 17th International Workshop on Room-Temperature Semiconductor X-ray and Gamma-ray Detectors, RTSD 2010 - Knoxville, TN, United States
Duration: Oct 30 2010Nov 6 2010

Other

Other2010 IEEE Nuclear Science Symposium, Medical Imaging Conference, NSS/MIC 2010 and 17th International Workshop on Room-Temperature Semiconductor X-ray and Gamma-ray Detectors, RTSD 2010
CountryUnited States
CityKnoxville, TN
Period10/30/1011/6/10

ASJC Scopus subject areas

  • Radiation
  • Nuclear and High Energy Physics
  • Radiology Nuclear Medicine and imaging

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    Zhou, J., & Qi, J. (2010). Efficient system modeling of a high-resolution zoom-in PET scanner. In IEEE Nuclear Science Symposium Conference Record (pp. 3501-3505). [5874457] https://doi.org/10.1109/NSSMIC.2010.5874457