Efficient iterative image reconstruction algorithm for dedicated breast CT

Natalia Antropova, Adrian Sanchez, Ingrid S. Reiser, Emil Y. Sidky, John M Boone, Xiaochuan Pan

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Scopus citations

Abstract

Dedicated breast computed tomography (bCT) is currently being studied as a potential screening method for breast cancer. The X-ray exposure is set low to achieve an average glandular dose comparable to that of mammography, yielding projection data that contains high levels of noise. Iterative image reconstruction (IIR) algorithms may be well-suited for the system since they potentially reduce the effects of noise in the reconstructed images. However, IIR outcomes can be difficult to control since the algorithm parameters do not directly correspond to the image properties. Also, IIR algorithms are computationally demanding and have optimal parameter settings that depend on the size and shape of the breast and positioning of the patient. In this work, we design an efficient IIR algorithm with meaningful parameter specifications and that can be used on a large, diverse sample of bCT cases. The flexibility and efficiency of this method comes from having the final image produced by a linear combination of two separately reconstructed images - one containing gray level information and the other with enhanced high frequency components. Both of the images result from few iterations of separate IIR algorithms. The proposed algorithm depends on two parameters both of which have a well-defined impact on image quality. The algorithm is applied to numerous bCT cases from a dedicated bCT prototype system developed at University of California, Davis.

Original languageEnglish (US)
Title of host publicationMedical Imaging 2016: Physics of Medical Imaging
PublisherSPIE
Volume9783
ISBN (Electronic)9781510600188
DOIs
StatePublished - 2016
EventMedical Imaging 2016: Physics of Medical Imaging - San Diego, United States
Duration: Feb 28 2016Mar 2 2016

Other

OtherMedical Imaging 2016: Physics of Medical Imaging
CountryUnited States
CitySan Diego
Period2/28/163/2/16

Keywords

  • breast cancer
  • dedicated breast CT
  • iterative image reconstruction
  • robustness

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

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