Efficient chemoenzymatic synthesis of sialyl Tn-antigens and derivatives

Li Ding, Hai Yu, Kam Lau, Yanhong Li, Saddam Muthana, Junru Wang, Xi Chen

Research output: Contribution to journalArticle

27 Scopus citations

Abstract

An N-terminal and C-terminal truncated recombinant α2-6- sialyltransferase cloned from Photobacterium sp. JH-ISH-224, Psp2,6ST(15-501)-His 6, was shown to be an efficient catalyst for one-pot three-enzyme synthesis of sialyl Tn (STn) antigens and derivatives containing natural and non-natural sialic acid forms.

Original languageEnglish (US)
Pages (from-to)8691-8693
Number of pages3
JournalChemical Communications
Volume47
Issue number30
DOIs
StatePublished - Aug 14 2011

ASJC Scopus subject areas

  • Metals and Alloys
  • Materials Chemistry
  • Surfaces, Coatings and Films
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Catalysis
  • Chemistry(all)

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