Efficacy of tolciclate solution in patients with tinea pedis

E. C. Gomez; A. C. Huntley; Roslyn Rivkah Isseroff; J. Tanji

Efficacy of tolciclate solution in patients with tinea pedis

E. C. Gomez, A. C. Huntley, Roslyn Rivkah Isseroff, J. Tanji

Dermatology

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Forty patients with tinea pedis were treated for six weeks in a double-blind study with a tolciclate or placebo solution. The tolciclate solution demonstrated moderate efficacy compared with placebo. The finding of positive KOH preparations in a significant number of tolciclate-treated patients with persistently negative cultures suggests that the vehicle used (polyethylene glycol-400) may not provide adequate penetration of this effective antifungal agent. No adverse effects were noted.

Original language	English (US)
Pages (from-to)	694-699
Number of pages	6
Journal	Clinical Therapeutics
Volume	8
Issue number	6
State	Published - 1986

ASJC Scopus subject areas

Pharmacology

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title = "Efficacy of tolciclate solution in patients with tinea pedis",

abstract = "Forty patients with tinea pedis were treated for six weeks in a double-blind study with a tolciclate or placebo solution. The tolciclate solution demonstrated moderate efficacy compared with placebo. The finding of positive KOH preparations in a significant number of tolciclate-treated patients with persistently negative cultures suggests that the vehicle used (polyethylene glycol-400) may not provide adequate penetration of this effective antifungal agent. No adverse effects were noted.",

author = "Gomez, {E. C.} and Huntley, {A. C.} and Isseroff, {Roslyn Rivkah} and J. Tanji",

year = "1986",

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AU - Gomez, E. C.

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AU - Isseroff, Roslyn Rivkah

AU - Tanji, J.

PY - 1986

Y1 - 1986

N2 - Forty patients with tinea pedis were treated for six weeks in a double-blind study with a tolciclate or placebo solution. The tolciclate solution demonstrated moderate efficacy compared with placebo. The finding of positive KOH preparations in a significant number of tolciclate-treated patients with persistently negative cultures suggests that the vehicle used (polyethylene glycol-400) may not provide adequate penetration of this effective antifungal agent. No adverse effects were noted.

AB - Forty patients with tinea pedis were treated for six weeks in a double-blind study with a tolciclate or placebo solution. The tolciclate solution demonstrated moderate efficacy compared with placebo. The finding of positive KOH preparations in a significant number of tolciclate-treated patients with persistently negative cultures suggests that the vehicle used (polyethylene glycol-400) may not provide adequate penetration of this effective antifungal agent. No adverse effects were noted.

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Efficacy of tolciclate solution in patients with tinea pedis

Abstract

ASJC Scopus subject areas

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