Efficacy of tolciclate solution in patients with tinea pedis

E. C. Gomez, A. C. Huntley, Roslyn Rivkah Isseroff, J. Tanji

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

Forty patients with tinea pedis were treated for six weeks in a double-blind study with a tolciclate or placebo solution. The tolciclate solution demonstrated moderate efficacy compared with placebo. The finding of positive KOH preparations in a significant number of tolciclate-treated patients with persistently negative cultures suggests that the vehicle used (polyethylene glycol-400) may not provide adequate penetration of this effective antifungal agent. No adverse effects were noted.

Original languageEnglish (US)
Pages (from-to)694-699
Number of pages6
JournalClinical Therapeutics
Volume8
Issue number6
StatePublished - 1986

ASJC Scopus subject areas

  • Pharmacology

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    Gomez, E. C., Huntley, A. C., Isseroff, R. R., & Tanji, J. (1986). Efficacy of tolciclate solution in patients with tinea pedis. Clinical Therapeutics, 8(6), 694-699.