Abstract
A prospective study was done to compare the efficacy of gastric emptying achieved by gastric lavage (GL) with that of ipecac-induced emesis (IE) in victims of drug overdose. Thiamine was used as a marker of recovery in gastric samples, as measured by ion exchange/ion pair high-performance liquid chromatography. There were 51 patients in the IE group and 37 in the GL group. GL produced a higher mean per cent recovery of thiamine than did IE (90% ± 34% compared with 50% ± 35%). There was a significant difference between the two groups (P < .001). Recovery of thiamine was more than 70% in 28% of the IE patients, and exceeded 70% in 75% of GL patients. When gastric emptying is desired for management of the adult overdose victim, the use of GL maximizes the chance of recovering unabsorbed liquid drugs from the stomach.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 692-698 |
| Number of pages | 7 |
| Journal | Annals of Emergency Medicine |
| Volume | 15 |
| Issue number | 6 |
| DOIs | |
| State | Published - 1986 |
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Keywords
- emptying
- gastric
- ipecac
- lavage
ASJC Scopus subject areas
- Emergency Medicine
Cite this
Efficacy of gastric emptying : Gastric lavage versus emesis induced with ipecac. / Auerbach, Paul S.; Osterloh, John; Braun, Odelia; Paul, Hu; Geehr, Edward C.; Kizer, Kenneth W; McKinney, Howard.
In: Annals of Emergency Medicine, Vol. 15, No. 6, 1986, p. 692-698.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Efficacy of gastric emptying
T2 - Gastric lavage versus emesis induced with ipecac
AU - Auerbach, Paul S.
AU - Osterloh, John
AU - Braun, Odelia
AU - Paul, Hu
AU - Geehr, Edward C.
AU - Kizer, Kenneth W
AU - McKinney, Howard
PY - 1986
Y1 - 1986
N2 - A prospective study was done to compare the efficacy of gastric emptying achieved by gastric lavage (GL) with that of ipecac-induced emesis (IE) in victims of drug overdose. Thiamine was used as a marker of recovery in gastric samples, as measured by ion exchange/ion pair high-performance liquid chromatography. There were 51 patients in the IE group and 37 in the GL group. GL produced a higher mean per cent recovery of thiamine than did IE (90% ± 34% compared with 50% ± 35%). There was a significant difference between the two groups (P < .001). Recovery of thiamine was more than 70% in 28% of the IE patients, and exceeded 70% in 75% of GL patients. When gastric emptying is desired for management of the adult overdose victim, the use of GL maximizes the chance of recovering unabsorbed liquid drugs from the stomach.
AB - A prospective study was done to compare the efficacy of gastric emptying achieved by gastric lavage (GL) with that of ipecac-induced emesis (IE) in victims of drug overdose. Thiamine was used as a marker of recovery in gastric samples, as measured by ion exchange/ion pair high-performance liquid chromatography. There were 51 patients in the IE group and 37 in the GL group. GL produced a higher mean per cent recovery of thiamine than did IE (90% ± 34% compared with 50% ± 35%). There was a significant difference between the two groups (P < .001). Recovery of thiamine was more than 70% in 28% of the IE patients, and exceeded 70% in 75% of GL patients. When gastric emptying is desired for management of the adult overdose victim, the use of GL maximizes the chance of recovering unabsorbed liquid drugs from the stomach.
KW - emptying
KW - gastric
KW - ipecac
KW - lavage
UR - http://www.scopus.com/inward/record.url?scp=0022553656&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0022553656&partnerID=8YFLogxK
U2 - 10.1016/S0196-0644(86)80427-9
DO - 10.1016/S0196-0644(86)80427-9
M3 - Article
VL - 15
SP - 692
EP - 698
JO - Annals of Emergency Medicine
JF - Annals of Emergency Medicine
SN - 0196-0644
IS - 6
ER -