Efficacy of gastric emptying: Gastric lavage versus emesis induced with ipecac

Paul S. Auerbach; John Osterloh; Odelia Braun; Hu Paul; Edward C. Geehr; Kenneth W Kizer; Howard McKinney

doi:10.1016/S0196-0644(86)80427-9

Efficacy of gastric emptying: Gastric lavage versus emesis induced with ipecac

Paul S. Auerbach, John Osterloh, Odelia Braun, Hu Paul, Edward C. Geehr, Kenneth W Kizer, Howard McKinney

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Abstract

A prospective study was done to compare the efficacy of gastric emptying achieved by gastric lavage (GL) with that of ipecac-induced emesis (IE) in victims of drug overdose. Thiamine was used as a marker of recovery in gastric samples, as measured by ion exchange/ion pair high-performance liquid chromatography. There were 51 patients in the IE group and 37 in the GL group. GL produced a higher mean per cent recovery of thiamine than did IE (90% ± 34% compared with 50% ± 35%). There was a significant difference between the two groups (P < .001). Recovery of thiamine was more than 70% in 28% of the IE patients, and exceeded 70% in 75% of GL patients. When gastric emptying is desired for management of the adult overdose victim, the use of GL maximizes the chance of recovering unabsorbed liquid drugs from the stomach.

Original language	English (US)
Pages (from-to)	692-698
Number of pages	7
Journal	Annals of Emergency Medicine
Volume	15
Issue number	6
DOIs	https://doi.org/10.1016/S0196-0644(86)80427-9
State	Published - 1986

Keywords

emptying
gastric
ipecac
lavage

ASJC Scopus subject areas

Emergency Medicine

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Auerbach, P. S., Osterloh, J., Braun, O., Paul, H., Geehr, E. C., Kizer, K. W., & McKinney, H. (1986). Efficacy of gastric emptying: Gastric lavage versus emesis induced with ipecac. Annals of Emergency Medicine, 15(6), 692-698. https://doi.org/10.1016/S0196-0644(86)80427-9

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abstract = "A prospective study was done to compare the efficacy of gastric emptying achieved by gastric lavage (GL) with that of ipecac-induced emesis (IE) in victims of drug overdose. Thiamine was used as a marker of recovery in gastric samples, as measured by ion exchange/ion pair high-performance liquid chromatography. There were 51 patients in the IE group and 37 in the GL group. GL produced a higher mean per cent recovery of thiamine than did IE (90% ± 34% compared with 50% ± 35%). There was a significant difference between the two groups (P < .001). Recovery of thiamine was more than 70% in 28% of the IE patients, and exceeded 70% in 75% of GL patients. When gastric emptying is desired for management of the adult overdose victim, the use of GL maximizes the chance of recovering unabsorbed liquid drugs from the stomach.",

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AU - Auerbach, Paul S.

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AU - Kizer, Kenneth W

AU - McKinney, Howard

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AB - A prospective study was done to compare the efficacy of gastric emptying achieved by gastric lavage (GL) with that of ipecac-induced emesis (IE) in victims of drug overdose. Thiamine was used as a marker of recovery in gastric samples, as measured by ion exchange/ion pair high-performance liquid chromatography. There were 51 patients in the IE group and 37 in the GL group. GL produced a higher mean per cent recovery of thiamine than did IE (90% ± 34% compared with 50% ± 35%). There was a significant difference between the two groups (P < .001). Recovery of thiamine was more than 70% in 28% of the IE patients, and exceeded 70% in 75% of GL patients. When gastric emptying is desired for management of the adult overdose victim, the use of GL maximizes the chance of recovering unabsorbed liquid drugs from the stomach.

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KW - ipecac

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