Efficacy of gastric emptying: Gastric lavage versus emesis induced with ipecac

Paul S. Auerbach; John Osterloh; Odelia Braun; Hu Paul; Edward C. Geehr; Kenneth W Kizer; Howard McKinney

doi:10.1016/S0196-0644(86)80427-9

Efficacy of gastric emptying: Gastric lavage versus emesis induced with ipecac

Paul S. Auerbach, John Osterloh, Odelia Braun, Hu Paul, Edward C. Geehr, Kenneth W Kizer, Howard McKinney

Nursing

Research output: Contribution to journal › Article › peer-review

53 Scopus citations

Abstract

A prospective study was done to compare the efficacy of gastric emptying achieved by gastric lavage (GL) with that of ipecac-induced emesis (IE) in victims of drug overdose. Thiamine was used as a marker of recovery in gastric samples, as measured by ion exchange/ion pair high-performance liquid chromatography. There were 51 patients in the IE group and 37 in the GL group. GL produced a higher mean per cent recovery of thiamine than did IE (90% ± 34% compared with 50% ± 35%). There was a significant difference between the two groups (P < .001). Recovery of thiamine was more than 70% in 28% of the IE patients, and exceeded 70% in 75% of GL patients. When gastric emptying is desired for management of the adult overdose victim, the use of GL maximizes the chance of recovering unabsorbed liquid drugs from the stomach.

Original language	English (US)
Pages (from-to)	692-698
Number of pages	7
Journal	Annals of Emergency Medicine
Volume	15
Issue number	6
DOIs	https://doi.org/10.1016/S0196-0644(86)80427-9
State	Published - 1986

Keywords

emptying
gastric
ipecac
lavage

ASJC Scopus subject areas

Emergency Medicine

Access to Document

10.1016/S0196-0644(86)80427-9

Fingerprint Dive into the research topics of 'Efficacy of gastric emptying: Gastric lavage versus emesis induced with ipecac'. Together they form a unique fingerprint.

Cite this

@article{49de991d11264c61b0cf0b8d125ea8d7,

title = "Efficacy of gastric emptying: Gastric lavage versus emesis induced with ipecac",

abstract = "A prospective study was done to compare the efficacy of gastric emptying achieved by gastric lavage (GL) with that of ipecac-induced emesis (IE) in victims of drug overdose. Thiamine was used as a marker of recovery in gastric samples, as measured by ion exchange/ion pair high-performance liquid chromatography. There were 51 patients in the IE group and 37 in the GL group. GL produced a higher mean per cent recovery of thiamine than did IE (90% ± 34% compared with 50% ± 35%). There was a significant difference between the two groups (P < .001). Recovery of thiamine was more than 70% in 28% of the IE patients, and exceeded 70% in 75% of GL patients. When gastric emptying is desired for management of the adult overdose victim, the use of GL maximizes the chance of recovering unabsorbed liquid drugs from the stomach.",

keywords = "emptying, gastric, ipecac, lavage",

author = "Auerbach, {Paul S.} and John Osterloh and Odelia Braun and Hu Paul and Geehr, {Edward C.} and Kizer, {Kenneth W} and Howard McKinney",

year = "1986",

doi = "10.1016/S0196-0644(86)80427-9",

language = "English (US)",

volume = "15",

pages = "692--698",

journal = "Annals of Emergency Medicine",

issn = "0196-0644",

publisher = "Mosby Inc.",

number = "6",

}

TY - JOUR

T1 - Efficacy of gastric emptying

T2 - Gastric lavage versus emesis induced with ipecac

AU - Auerbach, Paul S.

AU - Osterloh, John

AU - Braun, Odelia

AU - Paul, Hu

AU - Geehr, Edward C.

AU - Kizer, Kenneth W

AU - McKinney, Howard

PY - 1986

Y1 - 1986

N2 - A prospective study was done to compare the efficacy of gastric emptying achieved by gastric lavage (GL) with that of ipecac-induced emesis (IE) in victims of drug overdose. Thiamine was used as a marker of recovery in gastric samples, as measured by ion exchange/ion pair high-performance liquid chromatography. There were 51 patients in the IE group and 37 in the GL group. GL produced a higher mean per cent recovery of thiamine than did IE (90% ± 34% compared with 50% ± 35%). There was a significant difference between the two groups (P < .001). Recovery of thiamine was more than 70% in 28% of the IE patients, and exceeded 70% in 75% of GL patients. When gastric emptying is desired for management of the adult overdose victim, the use of GL maximizes the chance of recovering unabsorbed liquid drugs from the stomach.

AB - A prospective study was done to compare the efficacy of gastric emptying achieved by gastric lavage (GL) with that of ipecac-induced emesis (IE) in victims of drug overdose. Thiamine was used as a marker of recovery in gastric samples, as measured by ion exchange/ion pair high-performance liquid chromatography. There were 51 patients in the IE group and 37 in the GL group. GL produced a higher mean per cent recovery of thiamine than did IE (90% ± 34% compared with 50% ± 35%). There was a significant difference between the two groups (P < .001). Recovery of thiamine was more than 70% in 28% of the IE patients, and exceeded 70% in 75% of GL patients. When gastric emptying is desired for management of the adult overdose victim, the use of GL maximizes the chance of recovering unabsorbed liquid drugs from the stomach.

KW - emptying

KW - gastric

KW - ipecac

KW - lavage

UR - http://www.scopus.com/inward/record.url?scp=0022553656&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0022553656&partnerID=8YFLogxK

U2 - 10.1016/S0196-0644(86)80427-9

DO - 10.1016/S0196-0644(86)80427-9

M3 - Article

C2 - 2871787

AN - SCOPUS:0022553656

VL - 15

SP - 692

EP - 698

JO - Annals of Emergency Medicine

JF - Annals of Emergency Medicine

SN - 0196-0644

IS - 6

ER -