Efficacy of florfenicol for treatment of naturally occurring infectious bovine keratoconjunctivitis

John A Angelos, Erica L. Dueger, Lisle W. George, Tracey K. Carrier, Judy E. Mihalyi, Sallie B. Cosgrove, John C. Johnson

Research output: Contribution to journalArticlepeer-review

39 Scopus citations

Abstract

Objective - To determine the efficacy of florfenicol for treatment of calves with naturally occurring infectious bovine keratoconjunctivitis (IBK). Design - Randomized controlled field trial. Animals - 63 beef calves and 80 dairy calves between 4 and 12 months of age. Procedure - Calves were randomly assigned to 1 of 3 treatment groups. Calves in the SC treatment group received a single dose of florfenicol (40 mg/kg [18.2 mg/lb] of body weight), SC, on day 0. Calves in the IM treatment group received florfenicol (20 mg/kg [9.1 mg/lb]), IM, on days 0 and 2. Calves in the control group received injections of saline solution (0.9% NaCl), IM, on days 0 and 2. Calves were reevaluated every other day for 20 days after treatment. Results - Corneal ulcers healed by day 20 in 48 of 49 (98%) calves treated with florfenicol IM, 39 of 42 (93%) calves treated with florfenicol SC, and 33 of 52 (63%) control calves. Conclusions and Clinical Relevance - Florfenicol administered SC (1 dose) or IM (2 doses 48 hours apart) was effective for treatment of calves with naturally occurring IBK.

Original languageEnglish (US)
Pages (from-to)62-64
Number of pages3
JournalJournal of the American Veterinary Medical Association
Volume216
Issue number1
StatePublished - Jan 1 2000

ASJC Scopus subject areas

  • veterinary(all)

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