Efficacy of florfenicol for treatment of naturally occurring infectious bovine keratoconjunctivitis

John A Angelos, Erica L. Dueger, Lisle W. George, Tracey K. Carrier, Judy E. Mihalyi, Sallie B. Cosgrove, John C. Johnson

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

Objective - To determine the efficacy of florfenicol for treatment of calves with naturally occurring infectious bovine keratoconjunctivitis (IBK). Design - Randomized controlled field trial. Animals - 63 beef calves and 80 dairy calves between 4 and 12 months of age. Procedure - Calves were randomly assigned to 1 of 3 treatment groups. Calves in the SC treatment group received a single dose of florfenicol (40 mg/kg [18.2 mg/lb] of body weight), SC, on day 0. Calves in the IM treatment group received florfenicol (20 mg/kg [9.1 mg/lb]), IM, on days 0 and 2. Calves in the control group received injections of saline solution (0.9% NaCl), IM, on days 0 and 2. Calves were reevaluated every other day for 20 days after treatment. Results - Corneal ulcers healed by day 20 in 48 of 49 (98%) calves treated with florfenicol IM, 39 of 42 (93%) calves treated with florfenicol SC, and 33 of 52 (63%) control calves. Conclusions and Clinical Relevance - Florfenicol administered SC (1 dose) or IM (2 doses 48 hours apart) was effective for treatment of calves with naturally occurring IBK.

Original languageEnglish (US)
Pages (from-to)62-64
Number of pages3
JournalJournal of the American Veterinary Medical Association
Volume216
Issue number1
StatePublished - Jan 1 2000

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Infectious Keratoconjunctivitis
florfenicol
keratoconjunctivitis
calves
cattle
Corneal Ulcer
Therapeutics
sodium chloride
Sodium Chloride
dosage
Randomized Controlled Trials
Body Weight
dairy calves
Control Groups
Injections

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Angelos, J. A., Dueger, E. L., George, L. W., Carrier, T. K., Mihalyi, J. E., Cosgrove, S. B., & Johnson, J. C. (2000). Efficacy of florfenicol for treatment of naturally occurring infectious bovine keratoconjunctivitis. Journal of the American Veterinary Medical Association, 216(1), 62-64.

Efficacy of florfenicol for treatment of naturally occurring infectious bovine keratoconjunctivitis. / Angelos, John A; Dueger, Erica L.; George, Lisle W.; Carrier, Tracey K.; Mihalyi, Judy E.; Cosgrove, Sallie B.; Johnson, John C.

In: Journal of the American Veterinary Medical Association, Vol. 216, No. 1, 01.01.2000, p. 62-64.

Research output: Contribution to journalArticle

Angelos, JA, Dueger, EL, George, LW, Carrier, TK, Mihalyi, JE, Cosgrove, SB & Johnson, JC 2000, 'Efficacy of florfenicol for treatment of naturally occurring infectious bovine keratoconjunctivitis', Journal of the American Veterinary Medical Association, vol. 216, no. 1, pp. 62-64.
Angelos, John A ; Dueger, Erica L. ; George, Lisle W. ; Carrier, Tracey K. ; Mihalyi, Judy E. ; Cosgrove, Sallie B. ; Johnson, John C. / Efficacy of florfenicol for treatment of naturally occurring infectious bovine keratoconjunctivitis. In: Journal of the American Veterinary Medical Association. 2000 ; Vol. 216, No. 1. pp. 62-64.
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