Effects of race and ethnicity on the incidence of venous thromboembolism

Research output: Contribution to journalArticle

174 Scopus citations

Abstract

Although there is strong evidence that the prevalence of venous thrombo-embolism (VTE) varies significantly among different ethnic/racial groups, the genetic, physiologic and/or clinical basis for these differences remain largely undefined. African-American patients have a significantly higher rate of incident VTE, particularly following exposure to a provoking risk factor such as surgery, medical illness, trauma, etc. In addition, African-Americans are more likely to be diagnosed with pulmonary embolism (PE) than deep-vein thrombosis (DVT) compared to Caucasian and other racial groups. On the other extreme, Asians/Pacific Islanders have a 70% lower prevalence of VTE and this is true for both idiopathic VTE and provoked, or 'secondary', VTE. Hispanics have a significantly lower prevalence of VTE compared to Caucasians, but higher than Asians/Pacific Islanders. The incidence of recurrent VTE varies depending on gender, type of thromboembolic event and race. Further research is needed in order to determine the fundamental differences between racial/ethnic groups that explain the observed differences in the prevalence of VTE. Race/ethnicity should be considered an important factor in the risk-stratification of patients with suspected VTE or patients at some risk for developing VTE.

Original languageEnglish (US)
JournalThrombosis Research
Volume123
Issue numberSUPPL. 4
DOIs
StatePublished - 2009

Keywords

  • Deep-vein thrombosis
  • Disparities
  • Epidemiology
  • Pulmonary embolism
  • Race
  • Risk factors
  • Venous thromboembolism

ASJC Scopus subject areas

  • Hematology

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