Effects of ozone exposure on the lungs and the erythrocytes of rats and monkeys: relative biochemical changes

C. K. Chow, M. G. Mustafa, Carroll E Cross, B. K. Tarkington

Research output: Chapter in Book/Report/Conference proceedingChapter

25 Citations (Scopus)

Abstract

Ozone exposure (0.5 p.p.m., 8 hours daily for 7 days) resulted in a 20-26% (P < 0.05) increase in the level of reduced glutathione (GSH), and the activities of the GSH peroxidase system in rat lungs. The increases were of smaller magnitude (10-15%) in the lungs of ozone exposed monkeys. No significant changes were observed in these parameters in the erythrocytes of ozone exposed and control animals of the two species. The results suggest that rats may be more sensitive to ozone than monkeys in terms of biochemical lesions in the lung, and that ozone effects are manifested primarily in the lung.

Original languageEnglish (US)
Title of host publicationENVIRONM.PHYSIOL.BIOCHEM.
Pages142-146
Number of pages5
Volume5
Edition3
StatePublished - 1975

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Ozone
Haplorhini
Erythrocytes
Lung
Peroxidase
Glutathione

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Chow, C. K., Mustafa, M. G., Cross, C. E., & Tarkington, B. K. (1975). Effects of ozone exposure on the lungs and the erythrocytes of rats and monkeys: relative biochemical changes. In ENVIRONM.PHYSIOL.BIOCHEM. (3 ed., Vol. 5, pp. 142-146)

Effects of ozone exposure on the lungs and the erythrocytes of rats and monkeys : relative biochemical changes. / Chow, C. K.; Mustafa, M. G.; Cross, Carroll E; Tarkington, B. K.

ENVIRONM.PHYSIOL.BIOCHEM.. Vol. 5 3. ed. 1975. p. 142-146.

Research output: Chapter in Book/Report/Conference proceedingChapter

Chow, CK, Mustafa, MG, Cross, CE & Tarkington, BK 1975, Effects of ozone exposure on the lungs and the erythrocytes of rats and monkeys: relative biochemical changes. in ENVIRONM.PHYSIOL.BIOCHEM.. 3 edn, vol. 5, pp. 142-146.
Chow CK, Mustafa MG, Cross CE, Tarkington BK. Effects of ozone exposure on the lungs and the erythrocytes of rats and monkeys: relative biochemical changes. In ENVIRONM.PHYSIOL.BIOCHEM.. 3 ed. Vol. 5. 1975. p. 142-146
Chow, C. K. ; Mustafa, M. G. ; Cross, Carroll E ; Tarkington, B. K. / Effects of ozone exposure on the lungs and the erythrocytes of rats and monkeys : relative biochemical changes. ENVIRONM.PHYSIOL.BIOCHEM.. Vol. 5 3. ed. 1975. pp. 142-146
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