Effects of ozone exposure on the lungs and the erythrocytes of rats and monkeys: relative biochemical changes

C. K. Chow, M. G. Mustafa, Carroll E Cross, B. K. Tarkington

Research output: Chapter in Book/Report/Conference proceedingChapter

25 Scopus citations

Abstract

Ozone exposure (0.5 p.p.m., 8 hours daily for 7 days) resulted in a 20-26% (P < 0.05) increase in the level of reduced glutathione (GSH), and the activities of the GSH peroxidase system in rat lungs. The increases were of smaller magnitude (10-15%) in the lungs of ozone exposed monkeys. No significant changes were observed in these parameters in the erythrocytes of ozone exposed and control animals of the two species. The results suggest that rats may be more sensitive to ozone than monkeys in terms of biochemical lesions in the lung, and that ozone effects are manifested primarily in the lung.

Original languageEnglish (US)
Title of host publicationENVIRONM.PHYSIOL.BIOCHEM.
Pages142-146
Number of pages5
Volume5
Edition3
StatePublished - 1975

ASJC Scopus subject areas

  • Medicine(all)

Fingerprint Dive into the research topics of 'Effects of ozone exposure on the lungs and the erythrocytes of rats and monkeys: relative biochemical changes'. Together they form a unique fingerprint.

  • Cite this

    Chow, C. K., Mustafa, M. G., Cross, C. E., & Tarkington, B. K. (1975). Effects of ozone exposure on the lungs and the erythrocytes of rats and monkeys: relative biochemical changes. In ENVIRONM.PHYSIOL.BIOCHEM. (3 ed., Vol. 5, pp. 142-146)